Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Pharmacology of medical cannabis

MR Amin, DW Ali - Recent advances in cannabinoid physiology and …, 2019 - Springer
The Cannabis plant has been used for many of years as a medicinal agent in the relief of
pain and seizures. It contains approximately 540 natural compounds including more than …

Cannabinoids for medical use: a systematic review and meta-analysis

PF Whiting, RF Wolff, S Deshpande, M Di Nisio, S Duffy… - Jama, 2015 - jamanetwork.com
Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Efficacy of cannabis-based medicines for pain management: a systematic review and meta-analysis of randomized controlled trials

J Aviram, G Samuelly-Leichtag - Pain physician, 2017 - search.proquest.com
BACKGROUND: The management of chronic pain is a complex challenge worldwide.
Cannabis-based medicines (CBMs) have proven to be efficient in reducing chronic pain …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Association between cannabis and psychosis: epidemiologic evidence

SH Gage, M Hickman, S Zammit - Biological psychiatry, 2016 - Elsevier
Associations between cannabis use and psychotic outcomes are consistently reported, but
establishing causality from observational designs can be problematic. We review the …

Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD)

MW Elmes, M Kaczocha, WT Berger, KN Leung… - Journal of Biological …, 2015 - ASBMB
Δ 9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana
(Cannabis) and may be formulated, individually or in combination in pharmaceuticals such …

Pharmacological management of persistent pain in older persons

American Geriatrics Society Panel on the … - Pain …, 2009 - academic.oup.com
Pain is a complex phenomenon caused by noxious sensory stimuli or neuropathological
mechanisms. An individual's memories, expectations, and emotions modify the experience …

[HTML][HTML] Inhaled cannabis for chronic neuropathic pain: a meta-analysis of individual patient data

MH Andreae, GM Carter, N Shaparin, K Suslov… - The Journal of …, 2015 - Elsevier
Chronic neuropathic pain, the most frequent condition affecting the peripheral nervous
system, remains underdiagnosed and difficult to treat. Inhaled cannabis may alleviate …

Systematic review of systematic reviews for medical cannabinoids: Pain, nausea and vomiting, spasticity, and harms

GM Allan, CR Finley, J Ton, D Perry, J Ramji… - Canadian Family …, 2018 - cfp.ca
Objective To determine the effects of medical cannabinoids on pain, spasticity, and nausea
and vomiting, and to identify adverse events. Data sources MEDLINE, the Cochrane …