Intravenous application of tranexamic acid in patients undergoing plastic surgery: a systematic review and meta-analysis with GRADE quality assessment

S Wang, J Yang, L Lin - Aesthetic Plastic Surgery, 2024 - Springer
Background Tranexamic acid (TXA) is a versatile antifibrinolytic agent that is widely used in
modern surgeries. This review assessed the safety and efficacy of intravenous (IV) TXA in …

Local Tranexamic Acid for Preventing Hemorrhage in Anticoagulated Patients Undergoing Dental and Minor Oral Procedures: A Systematic Review and Meta …

A Zaib, M Shaheryar, M Shakil, A Sarfraz, Z Sarfraz… - Healthcare, 2022 - mdpi.com
Dental procedures have posed challenges in managing anticoagulated patients due to early
reports of oral hemorrhage. This study aims to evaluate the risks of postoperative bleeding …

Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A

AW Strilchuk, WS Hur, P Batty, Y Sang… - Science Translational …, 2024 - science.org
Antifibrinolytic drugs are used extensively for on-demand treatment of severe acute
bleeding. Controlling fibrinolysis may also be an effective strategy to prevent or lessen …

Hemostatic polyurethane sponge containing kaolin, tannic acid, and tranexamic acid

S Darakhshan, F Goudarzi, S Mirzaie… - Polymer Engineering …, 2023 - Wiley Online Library
Currently, the need for research in the field of hemostatic materials seems to be a necessity.
The purpose of this study was to prepare and assess a hemostatic polyurethane (PU) …

Early posttraumatic brain injury tranexamic acid prevents blood-brain barrier hyperpermeability and improves surrogates of neuroclinical recovery

MC Culkin, P Bele, AP Georges, AJ Lopez… - Journal of Trauma …, 2023 - journals.lww.com
BACKGROUND Tranexamic acid (TXA) given early, but not late, after traumatic brain injury
(TBI) appears to improve survival. This may be partly related to TXA-driven profibrinolysis …

Missingness matters: a secondary analysis of thromboelastography measurements from a recent prehospital randomized tranexamic acid clinical trial

JK Donohue, N Iyanna, JM Lorence… - Trauma Surgery & …, 2024 - tsaco.bmj.com
Background Tranexamic acid (TXA) has been hypothesized to mitigate coagulopathy in
patients after traumatic injury. Despite previous prehospital clinical trials demonstrating a …

Prophylactic tranexamic acid during myomectomy: A systematic review and meta-analysis of randomized controlled trials

S Baradwan, B Hafidh, HM Latifah, A Gari… - European Journal of …, 2022 - Elsevier
Objective To conduct a systematic review and meta-analysis of randomized controlled trials
on the clinical efficacy and safety of prophylactic tranexamic acid (TXA) versus control …

Platelet-inspired intravenous nanomedicine for injury-targeted direct delivery of thrombin to augment hemostasis in coagulopathies

A Girish, K Jolly, N Alsaadi, M de la Fuente… - ACS …, 2022 - ACS Publications
Severe hemorrhage associated with trauma, surgery, and congenital or drug-induced
coagulopathies can be life-threatening and requires rapid hemostatic management via …

Evaluating the effect of tranexamic acid local injection on the intraoperative bleeding amount and the postoperative edema and ecchymosis in primary rhinoplasty …

R Vaghardoost, A Ahmadi Dahaj… - Aesthetic Plastic …, 2024 - Springer
Abstract Background and Aims The purpose of this study was assessing the effect of local
injection of tranexamic acid (TXA) on the amount of bleeding during the primary rhinoplasty …

Intra-operative Tranexamic Acid Administration Significantly Decreases Incidence of Postoperative Bleeding Without Increasing Venous Thromboembolism Risk After …

N Hossain, V Kaur, M Mahran, A Quddus… - Obesity Surgery, 2024 - Springer
Background There is evidence that tranexamic acid (TXA) reduces surgical bleeding and is
widely used in trauma, obstetrics and other specialties. This practice is less well-established …