Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (second update)
D Roos, DB Kuhns, A Maddalena, J Bustamante… - Blood Cells, Molecules …, 2010 - Elsevier
Chronic granulomatous Disease (CGD) is an immunodeficiency disorder affecting about 1 in
250,000 individuals. The disease is caused by mutations in the genes encoding the …
250,000 individuals. The disease is caused by mutations in the genes encoding the …
The NADPH‐dependent oxidase of phagocytes
WM Nauseef - Proceedings of the Association of American …, 1999 - Wiley Online Library
Polymorphonuclear leukocytes (PMNs) represent a prominent cellular element in the innate
immune system, serving to ingest exogenous particles and microbes and to kill …
immune system, serving to ingest exogenous particles and microbes and to kill …
Hematologically important mutations: X-linked chronic granulomatous disease (second update)
PG Heyworth, JT Curnutte, J Rae, D Noack… - Blood Cells, Molecules …, 2001 - Elsevier
The most common form of chronic granulomatous disease (CGD) is caused by mutations in
the X-linked gene (CYBB, located at Xp21. 1) for the protein gp91phox. This protein is one of …
the X-linked gene (CYBB, located at Xp21. 1) for the protein gp91phox. This protein is one of …
[HTML][HTML] Molecular quality control machinery contributes to the leukocyte NADPH oxidase deficiency in chronic granulomatous disease
SJ Lin, YF Huang, JY Chen, PG Heyworth… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Chronic granulomatous disease (CGD) is an inherited immunodeficiency disease caused by
defects in leukocyte NADPH oxidase. Various inherited defects in one of the membrane …
defects in leukocyte NADPH oxidase. Various inherited defects in one of the membrane …
Thapsigargin and flavin adenine dinucleotide ex vivo treatment rescues trafficking-defective gp91phox in chronic granulomatous disease leukocytes
YF Huang, SY Liu, CL Yen, PW Yang… - Free Radical Biology and …, 2009 - Elsevier
Mutations in leukocyte NADPH oxidase genes lead to defective respiratory burst in
leukocytes and cause chronic granulomatous diseases (CGD) in humans. The most …
leukocytes and cause chronic granulomatous diseases (CGD) in humans. The most …
[HTML][HTML] A novel mutation in the CYBB gene resulting in an unexpected pattern of exon skipping and chronic granulomatous disease
D Noack, PG Heyworth, JT Curnutte, J Rae… - Biochimica et Biophysica …, 1999 - Elsevier
Chronic granulomatous disease is a rare inherited disorder caused by non-existent or
severely decreased phagocyte superoxide production that results in a severe defect in host …
severely decreased phagocyte superoxide production that results in a severe defect in host …
Structure and regulation of NADPH oxidase of phagocytic leukocytes
PG Heyworth, JT Curnutte, JA Badwey - Molecular and cellular basis of …, 1999 - Springer
When phagocytic cells of the immune system (neutrophils, monocytes, macrophages, and
eosinophils) come into contact with opsonized microorganisms or a wide range of soluble …
eosinophils) come into contact with opsonized microorganisms or a wide range of soluble …
[PDF][PDF] Glucose-Oxidase-Liposomen zur Therapie der septischen Granulomatose: In-vitro-Funktionalität, Granulozyten-Targeting und Wirkung im Organismus
A Kimpfler - 2003 - freidok.uni-freiburg.de
Unspezifische Abwehrmechanismen sind in der Lage, bereits beim ersten Kontakt
Krankheitserreger oder Fremdstoffe auszuschalten. Diese Abwehrmaßnahmen sind gegen …
Krankheitserreger oder Fremdstoffe auszuschalten. Diese Abwehrmaßnahmen sind gegen …
慢性肉芽種病的基因突變對白血球NADPH 氧化酵素功能及分子品質管制的影響
林秀娟， 謝奇璋 - 2000 - nckur.lib.ncku.edu.tw
慢性肉芽腫病是吞噬性白血球呼吸爆發功能缺損的先天性免疫疾病. 瞭解引發這個疾病的基因
缺陷及發生疾病的分子機轉對病患的健康至為重要. 本研究探討使用流式細胞儀偵測細胞呼吸 …
缺陷及發生疾病的分子機轉對病患的健康至為重要. 本研究探討使用流式細胞儀偵測細胞呼吸 …
Method for enhancing leukocyte immune function
CK Shieh - US Patent 7,955,847, 2011 - Google Patents
The present invention provides a method for enhancing the immune function of leukocytes in
a Subject, which comprises the steps of:(a) isolating leukocytes from the Subject;(b) treating …
a Subject, which comprises the steps of:(a) isolating leukocytes from the Subject;(b) treating …