In a complex system of interrelated reactions, the heart converts chemical energy to
mechanical energy. Energy transfer is achieved through coordinated activation of enzymes …

Heart failure is a growing public health concern. Advanced heart failure is frequently
associated with severe muscle wasting, termed cardiac cachexia. This process is driven by …

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American
College of Cardiology Foundation/American Heart Association Task Force on Practice …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2011 and includes selected …

Background—Although metabolic reprogramming is critical in the pathogenesis of heart
failure, studies to date have focused principally on fatty acid and glucose metabolism …

Objectives: This randomized controlled multicenter trial evaluated coenzyme Q10 (CoQ10)
as adjunctive treatment in chronic heart failure (HF). Background: CoQ10 is an essential …

Continued improvement in medical and device therapy for heart failure (HF) has led to better
survival with this disease. Longer survival and increasing numbers of unhealthy lifestyle …

Aim Acute heart failure (AHF) critically deranges haemodynamic and metabolic
homoeostasis. Iron is a key micronutrient for homoeostasis maintenance. We hypothesized …

Background: The clinical significance of nutritional risk assessment in patients with heart
failure with preserved ejection fraction (HFpEF) remains undefined. Geriatric nutritional risk …

The increasing burden of cardiovascular disease (CVD) despite the progress in
management entails the need of more effective preventive and curative strategies. As dietary …