Lobular neoplasia (LN) is a term that encompasses both lobular carcinoma in situ and
atypical lobular hyperplasia. These lesions have been shown to constitute both risk …

Recent studies have reported germline CDH1 mutations in cases of lobular breast cancer
(LBC) not associated with the classical hereditary diffuse gastric cancer syndrome. A …

Flat epithelial atypia (FEA) is an emerging entity of uncertain clinical significance, and
outcome data are sparse. The aim of this study was to evaluate the clinicopathologic …

The histologic triad of tubular carcinoma (TC), columnar cell lesion (CCL), and lobular
carcinoma in situ (LCIS) has been recognized, but has not yet been fully characterized. The …

Columnar cell lesions of the breast are increasingly recognized at mammography for their
tendency to calcify. We studied 392 vacuum-assisted core biopsies performed solely for …

Flat epithelial atypia (FEA) may represent the earliest precursor of low-grade breast cancer
and often coexists with more advanced atypical proliferative breast lesions such as atypical …

On behalf of the NHS Breast Screening Programme Pathology Coordinating Group we
present recommendations for terminology and diagnostic criteria for a number of key areas …

The biological behavior and the optimal management of benign breast lesions with
uncertain malignant potential, the so-called B3 lesions, found in breast needle core biopsies …

Certain nonmalignant lesions encountered on percutaneous breast biopsies pose dilemmas
with regard to the most appropriate clinical management subsequent to needle biopsy (ie …

This study analyzes the interobserver variability in interpreting atypia on breast core needle
biopsies and in each category of atypia calculates the upgrade risk of carcinoma in the …