The role of microRNA in psoriasis: A review

X Jiang, R Shi, R Ma, X Tang, Y Gong… - Experimental …, 2023 - Wiley Online Library
Psoriasis is a chronic immune‐mediated inflammatory skin disease that involves a complex
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …

[HTML][HTML] MicroRNAs in several cutaneous autoimmune diseases: Psoriasis, cutaneous lupus erythematosus and atopic dermatitis

S Domingo, C Solé, T Moliné, B Ferrer… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) are endogenous small non-coding RNA molecules that regulate the
gene expression at a post-transcriptional level and participate in maintaining the correct cell …

Dysregulated epigenetic modifications in psoriasis

C Zeng, LC Tsoi, JE Gudjonsson - Experimental dermatology, 2021 - Wiley Online Library
The observed incidence of psoriasis has been gradually increasing over time (J Am Acad
Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear …

[HTML][HTML] miRNAs flowing up and down: the concerto of psoriasis

Y Xiuli, W Honglin - Frontiers in Medicine, 2021 - frontiersin.org
Psoriasis is a chronic immune-mediated skin disease, whose hallmarks include keratinocyte
hyperproliferation and CD4+ T cell subsets imbalance. Dysregulated microRNAs (miRNAs) …

MiR-223 regulates proliferation and apoptosis of IL-22-stimulated HaCat human keratinocyte cell lines via the PTEN/Akt pathway

R Wang, F Wang, H Cao, J Yang - Life sciences, 2019 - Elsevier
Psoriasis, a chronic inflammatory skin disorder disease, is closely associated with
hyperproliferation of keratinocytes. Upregulated miR-223 has been found in peripheral …

[HTML][HTML] MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis

Y Wu, L Liu, C Bian, Q Diao, MF Nisar, X Jiang… - Cell Communication and …, 2018 - Springer
Background The extensive involvement of microRNA (miRNA) in the pathophysiology of
psoriasis is well documented. However, in order for this information to be useful in …

[HTML][HTML] The Role of Epigenetic Factors in the Pathogenesis of Psoriasis

J Olejnik-Wojciechowska, D Boboryko… - International Journal of …, 2024 - mdpi.com
Psoriasis is a chronic inflammatory skin disease, the prevalence of which is increasing.
Genetic, genomic, and epigenetic changes play a significant role in the pathogenesis of …

[HTML][HTML] The role of microRNAs in epidermal barrier

AY Lee - International Journal of Molecular Sciences, 2020 - mdpi.com
MicroRNAs (miRNAs), which mostly cause target gene silencing via transcriptional
repression and degradation of target mRNAs, regulate a plethora of cellular activities, such …

Kochia scoparia Saponin Momordin Ic Modulates HaCaT Cell Proliferation and Apoptosis via the Wnt/β‐Catenin Pathway

M Luo, B Zeng, H Wang, Z Yang, Y Peng… - Evidence‐Based …, 2021 - Wiley Online Library
Psoriasis is a chronic, recurrent, immunoinflammatory disease. For a long period, Traditional
Chinese Medicine (TCM) is considered a reliable alternative therapy for patients with …

FGF19 sustains the high proliferative ability of keratinocytes in psoriasis through the regulation of Wnt/GSK‐3β/β‐catenin signalling via FGFR 4

X Yu, N Yan, Z Li, Y Hua, W Chen - Clinical and Experimental …, 2019 - Wiley Online Library
Accumulating evidence has shown that fibroblast growth factor 19 (FGF 19) plays an
important role in regulating cell proliferation. Psoriasis is characterized by the …