[HTML][HTML] Alterations of the skin and gut microbiome in psoriasis and psoriatic arthritis

I Olejniczak-Staruch, M Ciążyńska… - International journal of …, 2021 - mdpi.com
Numerous scientific studies in recent years have shown significant skin and gut dysbiosis
among patients with psoriasis. A significant decrease in microbiome alpha-diversity …

[HTML][HTML] Skin barrier dysregulation in psoriasis

A Orsmond, L Bereza-Malcolm, T Lynch… - International journal of …, 2021 - mdpi.com
The skin barrier is broadly composed of two elements—a physical barrier mostly localised in
the epidermis, and an immune barrier localised in both the dermis and epidermis. These two …

[HTML][HTML] Gut microbiota in psoriasis

MC Buhaș, LI Gavrilaș, R Candrea, A Cătinean… - Nutrients, 2022 - mdpi.com
Psoriasis is a chronic inflammatory skin disease with autoimmune pathogenic characteristics
and is caused by chronic inflammation, which results in uncontrolled keratinocyte growth …

[HTML][HTML] Psoriasis and gut microbiome—current state of art

K Polak, B Bergler-Czop, M Szczepanek… - International journal of …, 2021 - mdpi.com
Psoriasis is a chronic, immune-mediated inflammatory disease that affects around 125
million people worldwide. Several studies concerning the gut microbiota composition and its …

Biomarkers of disease progression in people with psoriasis: a scoping review

R Ramessur, M Corbett, D Marshall… - British Journal of …, 2022 - academic.oup.com
Background Identification of those at risk of more severe psoriasis and/or associated
morbidities offers opportunity for early intervention, reduced disease burden and more cost …

[HTML][HTML] The role of gut microbiome in inflammatory skin disorders: A systematic review

S Widhiati, D Purnomosari, T Wibawa… - Dermatology …, 2022 - ncbi.nlm.nih.gov
The close relationship between the intestine and the skin has been widely stated, seen from
gastrointestinal (GI) disorders often accompanied by skin manifestations. Exactly how the …

Psoriasis: Interplay between dysbiosis and host immune system

B Kapoor, M Gulati, P Rani, R Gupta - Autoimmunity Reviews, 2022 - Elsevier
With advancement in human microbiome research, an increasing number of scientific
evidences have endorsed the key role of both gut and skin microbiota in the pathogenesis of …

[HTML][HTML] Unlocking the potential of the human microbiome for identifying disease diagnostic biomarkers

R Hajjo, DA Sabbah, AQ Al Bawab - Diagnostics, 2022 - mdpi.com
The human microbiome encodes more than three million genes, outnumbering human
genes by more than 100 times, while microbial cells in the human microbiota outnumber …

[HTML][HTML] Paradoxical reactions to anti-TNFα and anti-IL-17 treatment in psoriasis patients: are skin and/or gut microbiota involved?

Z Jiraskova Zakostelska, Z Reiss… - Dermatology and …, 2023 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory disease primarily affecting the skin. It
is currently coming to light that patients with psoriasis have disrupted intestinal barrier and …

[HTML][HTML] Deciphering gut microbiota dysbiosis and corresponding genetic and metabolic dysregulation in psoriasis patients using metagenomics sequencing

S Xiao, G Zhang, C Jiang, X Liu, X Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Increasing evidence has shown that alterations in the intestinal microbiota play
an important role in the pathogenesis of psoriasis. The existing relevant studies focus on …