Causal associations between gut microbiota and psoriasis: a Mendelian randomization study

C Zang, J Liu, M Mao, W Zhu, W Chen, B Wei - Dermatology and Therapy, 2023 - Springer
Introduction Previous studies have proposed a possible gut–skin axis, and linked gut
microbiota to psoriasis risks. However, there is heterogeneity in existing evidence …

Efficacy of guselkumab, a selective IL-23 inhibitor, in preventing arthritis in a multicentre psoriasis at-risk cohort (PAMPA): protocol of a randomised, double-blind …

RH Haberman, KA MacFarlane, S Catron, J Samuels… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Psoriatic arthritis (PsA) is a complex, immune-mediated disease associated with
skin psoriasis that, if left untreated, can lead to joint destruction. Up to 30% of patients with …

Paradoxical reactions to anti-TNFα and anti-IL-17 treatment in psoriasis patients: are skin and/or gut microbiota involved?

Z Jiraskova Zakostelska, Z Reiss… - Dermatology and …, 2023 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory disease primarily affecting the skin. It
is currently coming to light that patients with psoriasis have disrupted intestinal barrier and …

Rutin attenuates inflammation by downregulating AGE-RAGE signaling pathway in psoriasis: Network pharmacology analysis and experimental evidence

M Wang, X Ma, C Gao, Y Luo, X Fei, Q Zheng… - International …, 2023 - Elsevier
Background Jueyin granules (JYG) is effective against psoriasis, but its utility components
are not clear. Rutin is the main monomer of JYG, its therapeutic effect and mechanism on …

Patients with psoriasis have a dysbiotic taxonomic and functional gut microbiota

T Todberg, A Egeberg, C Zachariae… - British Journal of …, 2022 - academic.oup.com
Background Accumulating evidence supports the findings of an altered gut microbiota in
patients with autoimmune disease. However, existing studies on the role of the gut …

Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice

H Shinno-Hashimoto, Y Hashimoto, Y Wei, L Chang… - Scientific Reports, 2021 - nature.com
Psoriasis is a chronic, inflammatory skin disease. Although the precise etiology of psoriasis
remains unclear, gut–microbiota axis might play a role in the pathogenesis of the disease …

Deciphering gut microbiota dysbiosis and corresponding genetic and metabolic dysregulation in psoriasis patients using metagenomics sequencing

S Xiao, G Zhang, C Jiang, X Liu, X Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Increasing evidence has shown that alterations in the intestinal microbiota play
an important role in the pathogenesis of psoriasis. The existing relevant studies focus on …

Regulation of psoriasis, colitis, and the intestinal microbiota by clusterin

YK Jun, HT Yoon, SH Kwon, UH Jo, JE Kim, YM Han… - Scientific reports, 2023 - nature.com
Psoriasis, a chronic and systemic inflammatory disorder characterized by activation of the
interleukin (IL)-23/IL-17 axis, may be associated with the intestinal microbiota through the so …

Vertical stratification in urban green space aerobiomes

JM Robinson, C Cando-Dumancela… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Exposure to a diverse environmental microbiome is thought to play an
important role in “educating” the immune system and facilitating competitive exclusion of …

Nutrition and rheumatoid arthritis in the 'omics' era

M Cassotta, TY Forbes-Hernandez, D Cianciosi… - Nutrients, 2021 - mdpi.com
Modern high-throughput 'omics' science tools (including genomics, transcriptomics,
proteomics, metabolomics and microbiomics) are currently being applied to nutritional …