Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Role of mitochondrial quality surveillance in myocardial infarction: from bench to bedside

H Zhou, J Ren, S Toan, D Mui - Ageing Research Reviews, 2021 - Elsevier
Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …

Hallmarks of cardiovascular ageing

M Abdellatif, PP Rainer, S Sedej… - Nature Reviews …, 2023 - nature.com
Normal circulatory function is a key determinant of disease-free life expectancy (healthspan).
Indeed, pathologies affecting the cardiovascular system, which are growing in prevalence …

[HTML][HTML] Ischemia/reperfusion injury revisited: an overview of the latest pharmacological strategies

ROS Soares, DM Losada, MC Jordani, P Évora… - International journal of …, 2019 - mdpi.com
Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

[HTML][HTML] Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

A Tarocco, N Caroccia, G Morciano… - Cell death & …, 2019 - nature.com
Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …

[PDF][PDF] Ca2+ fluxes and cancer

S Marchi, C Giorgi, L Galluzzi, P Pinton - Molecular cell, 2020 - cell.com
Ca 2+ ions are key second messengers in both excitable and non-excitable cells. Owing to
the rather pleiotropic nature of Ca 2+ transporters and other Ca 2+-binding proteins …

The role of mitochondrial dynamics in cardiovascular diseases

M Forte, L Schirone, P Ameri, C Basso… - British journal of …, 2021 - Wiley Online Library
The process of mitochondrial dynamics is emerging as a core player in cardiovascular
homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission …

[HTML][HTML] Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

[HTML][HTML] Mitophagy, mitochondrial dynamics, and homeostasis in cardiovascular aging

NN Wu, Y Zhang, J Ren - Oxidative Medicine and Cellular Longevity, 2019 - hindawi.com
Biological aging is an inevitable and independent risk factor for a wide array of chronic
diseases including cardiovascular and metabolic diseases. Ample evidence has established …