Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As
many other natural flavonoids, it is often found in combination with glycosides in many fruits …

Cold-inducible RNA-binding protein (CIRP) is an intracellular stress-response protein and a
type of damage-associated molecular pattern (DAMP) that responds to various stress …

Lead (Pb) is one of the most common heavy metal pollutants affecting living organisms. It
induces nephrotoxicity with significant alterations in renal structure and function. Luteolin …

Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which
continue to be responsible for up to 70% of death worldwide. Despite the ongoing …

Background: Acute kidney injury (AKI) is a common and potentially fatal complication
encountered during a variety of kidney surgeries. Renal ischemia/reperfusion (I/R) injury is …

Aims Cyclophosphamide is an alkylating agent with vast arrays of therapeutic activity.
Currently, its medical use is limited due to its numerous adverse events, including …

Background Luteolin (LUT) is a flavonoid found in vegetables and fruits that has diverse
functions. Doxorubicin (DOX) is an anthracycline antibiotic that is frequently used for the …

The natural polyphenols mangiferin and luteolin have free radical-scavenging properties,
induce the antioxidant gene program and down-regulate the expression of superoxide …

Acute kidney injury (AKI) has been increasingly reported in critically-ill COVID-19 patients.
Moreover, there was significant positive correlation between COVID-19 deaths and renal …

The aim of this study was to investigate the effects of arbutin (ARB) administration on
oxidative stress, inflammation, endoplasmic reticulum (ER) stress and apoptosis in an …