Safety of inhaled and intranasal corticosteroids: lessons for the new millennium

BJ Lipworth, CM Jackson - Drug Safety, 2000 - Springer
Although inhaled and intranasal corticosteroids are first-line therapy for asthma and allergic
rhinitis, there has recently been an increasing awareness of their propensity to produce …

Potential adverse effects of the inhaled corticosteroids

HW Kelly, HS Nelson - Journal of Allergy and Clinical Immunology, 2003 - Elsevier
The purpose of this review is to provide the clinician with an update on the potential adverse
effects caused by the inhaled corticosteroids (ICSs). The systemic effects of ICSs are a result …

Use of inhaled and oral corticosteroids and the long-term risk of cataract

JJ Wang, E Rochtchina, AG Tan, RG Cumming… - Ophthalmology, 2009 - Elsevier
OBJECTIVE:: Longitudinal associations between inhaled and oral corticosteroid use and 10-
year incident cataract were examined. DESIGN: Population-based cohort study …

Acute adrenal crisis in asthmatics treated with high-dose fluticasone propionate

GRG Todd, CL Acerini, JJ Buck… - European …, 2002 - Eur Respiratory Soc
Four cases of asthma (one adult, three children) developing acute adrenal crisis after
introduction of high-dose inhaled fluticasone proprionate are presented. The three children …

Effect of ciclesonide and fluticasone on hypothalamicpituitary-adrenal axis function in adults with mild-to-moderate persistent asthma

BJ Lipworth, MA Kaliner, CF LaForce, JW Baker… - Annals of Allergy …, 2005 - Elsevier
BACKGROUND: Despite their proven efficacy in the treatment and prevention of asthma
exacerbations, current inhaled corticosteroids carry safety concerns, especially adrenal …

Dose–response evaluation of the therapeutic index for inhaled budesonide in patients with mild-to-moderate asthma

AM Wilson, BJ Lipworth - The American journal of medicine, 2000 - Elsevier
PURPOSE: Inhaled corticosteroids have beneficial effects on pulmonary function and
inflammation in patients with asthma, but they also cause systemic adverse effects, such as …

Risk‐benefit value of inhaled glucocorticoids: a pharmacokinetic/pharmacodynamic perspective

S Rohatagi, S Appajosyula, H Derendorf… - The Journal of …, 2004 - Wiley Online Library
Inhaled glucocorticoids induce therapeutic and adverse systemic effects via the same types
of receptors. Analysis of the pharmacokinetic/pharmacodynamic parameters of inhaled …

布地奈德溶液雾化吸入治疗对喘息性支气管炎患儿呼吸道阻力的影响

孙树梅, 谢松敏 - 实用儿科临床杂志, 2007 - cqvip.com
目的研究布地奈德雾化溶液吸入治疗对喘息性支气管炎患儿呼吸道阻力(AR) 的影响.
方法喘息性支气管炎患儿56 例随机分为A 组(常规+ 布地奈德雾化溶液吸入治疗) 和B …

[HTML][HTML] History and future perspectives of treating asthma as a systemic and small airways disease

L Bjermer - Respiratory medicine, 2001 - Elsevier
Asthma is an inflammatory disorder in which the small airways of the lung play an important
role. There is also evidence for the systemic nature of asthma. No current method …

Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: a meta-analysis

GP Currie, SJ Fowler, BJ Lipworth - Annals of Allergy, Asthma & …, 2003 - Elsevier
BACKGROUND: There is a relatively steep dose-response curve for effects of inhaled
corticosteroids on conventional airway markers of asthmatic disease control. OBJECTIVES …