Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Older people often show auditory temporal processing deficits and speech-in-noise
intelligibility difficulties even when their audiogram is clinically normal. The causes of such …

Tinnitus, reduced sound-level tolerance, and difficulties hearing in noisy environments are
the most common complaints associated with sensorineural hearing loss in adult …

Resident cochlear macrophages rapidly migrate into the inner hair cell synaptic region and
directly contact the damaged synaptic connections after noise-induced synaptopathy …

Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …

Hearing loss caused by noise exposure, ototoxic drugs, or aging results from the loss of
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …

Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …

Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …

Objective: The purpose of this study was to identify the main factors that differentiate
listeners with clinically normal or “near-normal” hearing with regard to their speech-in-noise …

Many individuals with seemingly normal hearing abilities struggle to understand speech in
noisy backgrounds. To understand why this might be the case, we investigated the neural …