Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …

[HTML][HTML] Associated Bacterial Coinfections in COVID-19-Positive Patients

ER Boia, AR Huț, A Roi, RE Luca, IR Munteanu… - Medicina, 2023 - mdpi.com
Background and Objectives: The aim of this study was to identify specific rhino-and
oropharyngeal microbiological pathogens as well as associated comorbidities that favor …

[HTML][HTML] Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

YM Ali, NJ Lynch, P Khatri, IE Bamigbola… - Frontiers in …, 2022 - frontiersin.org
A high incidence of secondary Klebsiella pneumoniae and Staphylococcus aureus infection
were observed in patients with severe COVID-19. The cause of this predisposition to …

[HTML][HTML] Invasive fusariosis in a critically ill patient with severe COVID-19 pneumonia: A case report

F Barberis, MF Benedetti, MS de Abreu, SJ Pola… - Medical Mycology Case …, 2022 - Elsevier
Invasive fungal infections as aspergillosis and candidiasis are well-documented
complications in critically ill patients with acute respiratory distress syndrome due to COVID …

Мукормикоз у больных COVID-19 в России: результаты проспективного многоцентрового исследования

СН Хостелиди, ВА Зайцев, СА Вартанян… - Журнал …, 2022 - journal.niidi.ru
МУКОРМИКОЗ У БОЛЬНЫХ COVID-19 В РОССИИ: РЕЗУЛЬТАТЫ ПРОСПЕКТИВНОГО
МНОГОЦ Page 1 Оригинальное исследование Том 14, №2, 2022 ЖУРНАЛ …

[HTML][HTML] Does the fetus limit antibiotic treatment in pregnant patients with COVID-19?

T Ramírez-Lozada, MC Loranca-García… - Antibiotics, 2022 - mdpi.com
During pregnancy, there is a state of immune tolerance that predisposes them to viral
infection, causing maternal-fetal vulnerability to the adverse effects of COVID-19. Bacterial …

Identifying the risk factors of ICU-acquired fungal infections: clinical evidence from using machine learning

Y Zhao, Q Lai, H Tang, R Luo, Z He, W Huang… - Frontiers in …, 2024 - frontiersin.org
Background Fungal infections are associated with high morbidity and mortality in the
intensive care unit (ICU), but their diagnosis is difficult. In this study, machine learning was …

Parietal composition of Lichtheimia corymbifera: Differences between spore and germ tube stages and host-pathogen interactions

K Lecointe, P Coulon, F Krzewinski, R Charlet… - Medical …, 2023 - academic.oup.com
The molecular composition and structural organization of the cell wall of filamentous fungi
underlie the ability of the host to identify them as pathogens. Although the organization of the …

[HTML][HTML] Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS

FA Messina, A Benchetrit, A Bocassi, MM Romero… - Biomédica, 2023 - scielo.org.co
Introduction. Fungal infections in patients with COVID-19 was one of the most debated topics
during the pandemic. Objectives. To analyze the clinical characteristics and evolution of …

Molecular detection of Histoplasma capsulatum in organ samples from bats randomly captured in urban areas of Araraquara, São Paulo state, Brazil

JA Ruiz-Muñoz, G Rodríguez-Arellanes… - Epidemiology & …, 2024 - cambridge.org
The mycosis histoplasmosis is also considered a zoonosis that affects humans and other
mammalian species worldwide. Among the wild mammals predisposed to be infected with …