Immunological aspects of juvenile rheumatoid arthritis

K YOSHINO - Pediatrics International, 1993 - Wiley Online Library
This article reviews the evidence from recent studies on immunological abnormalities
associated with pathophysiologic mechanisms operating in three clinical subtypes of …

Defective autologous mixed lymphocyte reactions in patients with renal insufficiency—Evidence for cellular and serum factors

PA Frymoyer, FR Davey - Clinical Immunology and Immunopathology, 1985 - Elsevier
The autologous mixed lymphocyte reaction (AMLR) was studied in 10 patients who were
azotemic from renal diseases not considered to be immunologically mediated. These …

[56] Identification and characterization of human T lymphocyte antigens

PL Romain, O Acuto, SF Schlossman - Methods in enzymology, 1984 - Elsevier
Publisher Summary This chapter reviews that T lymphocytes play a central role in the
immune response by virtue of their ability to recognize antigens with a high degree of …

Activation of OKT4 suppressor cells in the autologous mixed lymphocyte reaction of patients with juvenile rheumatoid arthritis.

K Oen, D Krzekotowska - Clinical and experimental immunology, 1987 - ncbi.nlm.nih.gov
Activation of suppressor cells by the autologous mixed lymphocyte reaction (AMLR) was
studied in patients with juvenile rheumatoid arthritis (JRA). Isolated OKT4 cells were used as …

Analysis of the role of xenogeneic antigens in the proliferation of human T cells stimulated with autologous non-T cells and phytohemagglutinin-activated T cells

F Indiveri, M Scudeletti, D Pende, C Piccardo, I Pierri… - Cellular …, 1985 - Elsevier
Since conflicting results have been reported about the role of xenoantigens in the
proliferation of T cells stimulated with autologous non-T cells, the effect of the exposure of …

The autologous mixed lymphocyte reaction

S Gupta - Immunology of rheumatic diseases, 1985 - Springer
At the turn of the century, Ehrlich (1957) proposed that the immunity to autologous antigen is
highly abnormal and would result in a disease process. At midcentury, Burnet (1959) …

The human immunoregulatory T cell circuit: recent progress and its clinical implications

C Morimoto, SF Schlossman - The Keio Journal of Medicine, 1987 - jstage.jst.go.jp
The present studies indicate that both the heterogeneity and functional programs of human T
lymphocytes can be distinguished. Within the T4 subset, which is responsible for …

Peripheral but not thymic T cells participate in an autoreactive T cell network

DW Kennedy, ME Weksler, C Russo - Cellular immunology, 1988 - Elsevier
Splenic T cells proliferate in response to the anti-IA b reactive T cell hybridoma T 1.203 in an
H-2-restricted but MHC antigen-independent manner. We propose that this anti-idiotypic …

Dissection of the T-cell circuit with monoclonal antibodies

SF Schlossman - Medical Oncology and Tumor Pharmacotherapy, 1984 - Springer
The present studies indicate that one can dissect both the heterogeneity and functional
program of the human T-cell. These investigations indicate that late in thymic ontogeny the T …

Reconstitution of impaired autologous mixed lymphocyte reactivity in rheumatoid arthritis

E Keystone, L Poplonski, KM Snow, A Shore… - …, 1991 - Taylor & Francis
We examined the ability of recombinant IL-2 to reconstitute the autologous mixed
lymphocyte reaction (AMLR) defect in peripheral blood mononuclear cells (PBM) from …