[HTML][HTML] Toward regeneration of the heart: bioengineering strategies for immunomodulation

A Ferrini, MM Stevens, S Sattler… - Frontiers in …, 2019 - frontiersin.org
Myocardial Infarction (MI) is the most common cardiovascular disease. An average-sized MI
causes the loss of up to 1 billion cardiomyocytes and the adult heart lacks the capacity to …

[HTML][HTML] Macrophages: First guards in the prevention of cardiovascular diseases

MI Nasser, S Zhu, H Huang, M Zhao, B Wang, H Ping… - Life sciences, 2020 - Elsevier
Cardiovascular diseases (CVD) remain one of the leading causes of mortality worldwide,
especially in developing countries. It is widely known that severe inflammation can lead to …

Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches

SS Soni, AM D'Elia, CB Rodell - Drug delivery and translational research, 2023 - Springer
Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …

fibrosis and inflammation in tissue pathophysiology

I Chimenti, S Sattler, G del Monte-Nieto… - Frontiers in …, 2022 - frontiersin.org
Mammalian tissues react to damage by activating the highly specialized response of wound
healing. Acute inflammation is the first and fastest mechanism activated in the damaged …

[HTML][HTML] Lymphocytic subsets play distinct roles in heart diseases

J Wang, Y Duan, JPG Sluijter, J Xiao - Theranostics, 2019 - ncbi.nlm.nih.gov
Heart diseases are one of the leading causes of death for humans in the world. Increasing
evidence has shown that myocardial injury induced innate and adaptive immune responses …

Antiarrhythmic and Anti-Inflammatory Effects of Sacubitril/Valsartan on Post-Myocardial Infarction Scar

D Martínez-Falguera, J Aranyó, A Teis… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Sacubitril/valsartan (Sac/Val) is superior to angiotensin-converting enzyme
inhibitors in reducing the risk of heart failure hospitalization and cardiovascular death, but its …

[HTML][HTML] Takotsubo syndrome: latest addition to the expanding family of immune-mediated diseases?

S Sattler, LS Couch, SE Harding - JACC: Basic to Translational Science, 2018 - jacc.org
broken heart syndrome, is a severe and acute heart failure syndrome that often resolves
spontaneously but can also be associated with significant mortality. TTS predominantly …

Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease

E Wang, AL Pan, P Bagchi, S Rangaraju, NT Seyfried… - Biomolecules, 2024 - mdpi.com
DUSP4 is a member of the DUSP (dual-specificity phosphatase) subfamily that is selective
to the mitogen-activated protein kinases (MAPK) and has been implicated in a range of …

Takotsubo syndrome and rheumatic diseases—a critical systematic review

W Lin, SH Tay, A Mak - Rheumatology, 2021 - academic.oup.com
Since its description in 1990, Takotsubo syndrome (TTS), an acute cardiac condition
triggered by physical or emotional stress, has been believed to be related to catecholamine …

Impact of cardiac rehabilitation programs on left ventricular remodeling after acute myocardial infarction: Study Protocol Clinical Trial (SPIRIT Compliant)

MG Susca, R Hodas, T Benedek, I Benedek, M Chitu… - Medicine, 2020 - journals.lww.com
Conclusion: In conclusion, REHAB will be the first trial that will elucidate the impact of early
mobilization in the first period after AMI, as a first step of a complex cardiac rehabilitation …