Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy
KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
Piezocatalytic medicine: an emerging frontier using piezoelectric materials for biomedical applications
S Chen, P Zhu, L Mao, W Wu, H Lin, D Xu… - Advanced …, 2023 - Wiley Online Library
Emerging piezocatalysts have demonstrated their remarkable application potential in
diverse medical fields. In addition to their ultrahigh catalytic activities, their inherent and …
diverse medical fields. In addition to their ultrahigh catalytic activities, their inherent and …
Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects
S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …
fluorescent markers or for the detection of biomolecules owing to their good optical physical …
[HTML][HTML] Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
B Ji, M Wei, B Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
Cancer immunotherapy has made tremendous clinical progress in advanced-stage
malignancies. However, patients with various tumors exhibit a low response rate to …
malignancies. However, patients with various tumors exhibit a low response rate to …
Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …