Ruthenium-based photoactivated chemotherapy

S Bonnet - Journal of the American Chemical Society, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes form a vast family of molecules characterized by their
finely tuned photochemical and photophysical properties. Their ability to undergo excited …

Recent advances in noble metal complex based photodynamic therapy

Y Wu, S Li, Y Chen, W He, Z Guo - Chemical Science, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) utilizes light-activated photosensitizers (PSs) to generate toxic
species for therapeutics. It has become an emerging solution for cancer treatment because …

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Y Liu, P Bhattarai, Z Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …

Massively evoking immunogenic cell death by focused mitochondrial oxidative stress using an AIE luminogen with a twisted molecular structure

C Chen, X Ni, S Jia, Y Liang, X Wu, D Kong… - Advanced …, 2019 - Wiley Online Library
Immunogenic cell death (ICD) provides momentous theoretical principle for modern cancer
immunotherapy. However, the currently available ICD inducers are still very limited and …

Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

GSH‐Depleted PtCu3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy

X Zhong, X Wang, L Cheng, Y Tang… - Advanced Functional …, 2020 - Wiley Online Library
The ultrahigh concentration of glutathione (GSH) inside tumors destroys reactive oxygen
species (ROS)‐based therapy, improving the outcome of chemodynamic therapy (CDT) …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

Photodynamic therapy for hypoxic tumors: Advances and perspectives

L Huang, S Zhao, J Wu, L Yu, N Singh, K Yang… - Coordination Chemistry …, 2021 - Elsevier
Photodynamic therapy (PDT) has been a preferred clinical technology for treating superficial
tumors due to its advantages of high selectivity, non-invasiveness and negligible drug …

Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

Nanostructured phthalocyanine assemblies with efficient synergistic effect of type I photoreaction and photothermal action to overcome tumor hypoxia in photodynamic …

YY Zhao, L Zhang, Z Chen, BY Zheng… - Journal of the …, 2021 - ACS Publications
Most photodynamic therapy (PDT) paradigms work through the highly O2-dependent type II
photoreaction to generate singlet oxygen (1O2). The hypoxic microenvironment of solid …