Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function

S Tota, K Hanif, PK Kamat, AK Najmi, C Nath - Psychopharmacology, 2012 - Springer
Rational Inhibition of renin–angiotensin system (RAS) improves cognitive functions in
hypertensive patients. However, role of AT1 and AT2 receptors in memory impairment due to …

Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: role of cholinergic neurotransmission, cerebral …

S Tota, C Nath, AK Najmi, R Shukla, K Hanif - Behavioural Brain Research, 2012 - Elsevier
Evidences indicate that inhibition of central Renin angiotensin system (RAS) ameliorates
memory impairment in animals and humans. Earlier we have reported involvement of central …

[PDF][PDF] Cardiovascular risk factors as potential markers for mild cognitive impairment and Alzheimer's disease

A Ciobica, M Padurariu, W Bild, C Stefanescu - Psychiatria Danubina, 2011 - hrcak.srce.hr
CARDIOVASCULAR RISK FACTORS AS POTENTIAL MARKERS FOR MILD COGNITIVE
IMPAIRMENT AND ALZHEIMER’S DISEASE Page 1 340 Psychiatria Danubina, 2011; Vol. 23 …

Potential of protease inhibitor in 3-nitropropionic acid induced Huntington's disease like symptoms: mitochondrial dysfunction and neurodegeneration

A Hariharan, S Shetty, T Shirole, AG Jagtap - Neurotoxicology, 2014 - Elsevier
Huntington's disease (HD) is a genetic, neurodegenerative disorder mainly characterized by
motor dysfunction, cognitive decline and psychiatric disturbances. 3-Nitropropionic acid (3 …

The renin-angiotensin system and antihypertensive drugs in Alzheimer's disease: current standing of the angiotensin hypothesis?

PG Kehoe, PA Passmore - Journal of Alzheimer's Disease, 2012 - content.iospress.com
There is an urgent need to improve upon Alzheimer's disease (AD) treatments. Limitations of
existing drugs are that they target specific downstream neurochemical abnormalities while …

Neurovascular and cognitive failure in Alzheimer's disease: benefits of cardiovascular therapy

E Hamel, J Royea, B Ongali, XK Tong - Cellular and molecular …, 2016 - Springer
Alzheimer's disease (AD) is a multifactorial and multifaceted disease for which we currently
have very little to offer since there is no curative therapy, with only limited disease-modifying …

Current status of renin–aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease

EL Ashby, PG Kehoe - Expert opinion on investigational drugs, 2013 - Taylor & Francis
Introduction: Hypertension is a modifiable risk factor for Alzheimer's disease (AD) and other
dementias. Yet, despite this well-documented association, few of the current strategies to …

[HTML][HTML] The role of neurotrophins in psychopathology and cardiovascular diseases: psychosomatic connections

A László, L Lénárt, L Illésy, A Fekete… - Journal of Neural …, 2019 - Springer
Cardiovascular (CV) diseases and mood disorders are common public health problems
worldwide. Their connections are widely studied, and the role of neurotrophins (NTs) is …

[HTML][HTML] The Emerging Evidence for a Protective Role of Fucoidan from Laminaria japonica in Chronic Kidney Disease-Triggered Cognitive Dysfunction

Z Ma, Z Yang, X Feng, J Deng, C He, R Li, Y Zhao… - Marine Drugs, 2022 - mdpi.com
This study aimed to explore the mechanism of fucoidan in chronic kidney disease (CKD)-
triggered cognitive dysfunction. The adenine-induced ICR strain CKD mice model was …

An update of the role of renin angiotensin in cardiovascular homeostasis

E Farag, K Maheshwari, J Morgan, WAS Esa… - Anesthesia & …, 2015 - journals.lww.com
The renin angiotensin system (RAS) is thought to be the body's main vasoconstrictor system,
with physiological effects mediated via the interaction of angiotensin II with angiotensin I …