Compton imaging for medical applications

H Tashima, T Yamaya - Radiological Physics and Technology, 2022 - Springer
Compton imaging exploits inelastic scattering, known as Compton scattering, using a
Compton camera consisting of a scatterer detector in the front layer and an absorber …

Recent progress of astatine-211 in endoradiotherapy: Great advances from fundamental properties to targeted radiopharmaceuticals

F Li, Y Yang, J Liao, N Liu - Chinese Chemical Letters, 2022 - Elsevier
Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …

Medical application of particle and heavy ion transport code system PHITS

T Furuta, T Sato - Radiological Physics and Technology, 2021 - Springer
Abstract The Particle and Heavy Ion Transport code System (PHITS) is a general-purpose
Monte Carlo simulation code that has been applied in various areas of medical physics …

Targeted Alpha Therapy of Glioma Using 211At-Labeled Heterodimeric Peptide Targeting Both VEGFR and Integrins

W Liu, H Ma, R Liang, X Chen, H Li, T Lan… - Molecular …, 2022 - ACS Publications
Targeted radionuclide therapy based on α-emitters plays an increasingly important role in
cancer treatment. In this study, we proposed to apply a heterodimeric peptide (iRGD-C6-lys …

211At-Labeled Nanoscale Polydopamine Decorated with FAPI for Synergistic Targeted-Alpha Therapy and Photothermal Therapy of Glioma

F Li, H Ma, H Luo, G Shen, J Su, H Cai… - ACS Applied Nano …, 2024 - ACS Publications
How to boost the therapeutic efficiency is still the key to translation of anticancer
nanomedicine from preclinical investigations to clinical practice. In this work, we proposed to …

The performance study of developed cost-effective Compton Camera based on Ce: GAGG scintillator using experimental measurements and CCMod of GATE …

H Zarei, Y Nagao, K Yamamoto, M Itoh… - Journal of …, 2022 - iopscience.iop.org
In our previous work, a cost-effective Compton camera (CC) using Ce doped Gd 3 (Al, Ga) 5
O 12 (Ce: GAGG) scintillator consisting of two detectors, scatterer (20.8× 20.8× 5 mm 3) and …

ComptonNet: A direct reconstruction model for Compton camera

S Sato, KS Tanaka, J Kataoka - Applied Physics Letters, 2024 - pubs.aip.org
A Compton camera is a gamma-ray imaging device, especially in the sub-mega-electron volt
to higher than mega-electron volt range. Compton cameras have recently attracted attention …

Visualization of low-level gamma radiation sources using a low-cost, high-sensitivity, omnidirectional compton camera

H Muraishi, R Enomoto, H Katagiri, M Kagaya… - JoVE (Journal of …, 2020 - jove.com
We present experimental protocols for visualizing various low-level gamma radiation
sources in the ambient environment. Experiments were conducted by using a low-cost, high …

Development of an X-ray imaging camera for targeted radionuclide therapy with astatine-211

H Kusano, T Kusumoto, S Hasegawa… - Radiation Measurements, 2024 - Elsevier
The alpha-particle targeted radionuclide therapy (TRT) has been actively investigated for
cancer treatment, and astatine-211 (211 At) is one of the promising alpha-particle emitters …

Compton cameras and their applications

J Roser, F Hueso-González, A Ros… - Radiation Detection …, 2021 - taylorfrancis.com
Compton cameras are one of the tools employed for gamma-ray imaging. In these devices,
at least two distinguishable photon interactions are required, the first one being Compton …