Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

Graphene and its derivatives: Synthesis and application in the electrochemical detection of analytes in sweat

A Singh, A Ahmed, A Sharma, S Arya - Biosensors, 2022 - mdpi.com
Wearable sensors and invasive devices have been studied extensively in recent years as
the demand for real-time human healthcare applications and seamless human–machine …

Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies

M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …

Non-invasive drug delivery across the blood–brain barrier: a prospective analysis

SK Niazi - Pharmaceutics, 2023 - mdpi.com
Non-invasive drug delivery across the blood–brain barrier (BBB) represents a significant
advancement in treating neurological diseases. The BBB is a tightly packed layer of …

Neuro-nanotechnology: diagnostic and therapeutic nano-based strategies in applied neuroscience

L Shabani, M Abbasi, Z Azarnew, AM Amani… - Biomedical engineering …, 2023 - Springer
Artificial, de-novo manufactured materials (with controlled nano-sized characteristics) have
been progressively used by neuroscientists during the last several decades. The …

Molecular targeted therapy: a new avenue in glioblastoma treatment

O El Atat, R Naser, M Abdelkhalek… - Oncology …, 2022 - spandidos-publications.com
Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …

Transferrin-conjugated PLGA nanoparticles for Co-delivery of temozolomide and bortezomib to glioblastoma cells

MJ Ramalho, ID Torres, JA Loureiro… - ACS Applied Nano …, 2023 - ACS Publications
Glioblastoma (GBM) represents almost half of primary brain tumors, and its standard
treatment with the alkylating agent temozolomide (TMZ) is not curative. Treatment failure is …

Polymeric nanoparticles and nanogels: how do they interact with proteins?

A Sadeghi, S PourEskandar, E Askari, M Akbari - Gels, 2023 - mdpi.com
Polymeric nanomaterials, nanogels, and solid nanoparticles can be fabricated using single
or double emulsion methods. These materials hold great promise for various biomedical …

Nanoparticle strategies to improve the delivery of anticancer drugs across the blood–brain barrier to treat brain tumors

WJF Vanbilloen, JS Rechberger, JB Anderson… - Pharmaceutics, 2023 - mdpi.com
Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

Current update on transcellular brain drug delivery

B Pawar, N Vasdev, T Gupta, M Mhatre, A More… - Pharmaceutics, 2022 - mdpi.com
It is well known that the presence of a blood–brain barrier (BBB) makes drug delivery to the
brain more challenging. There are various mechanistic routes through which therapeutic …