The molecular and cellular basis of copper dysregulation and its relationship with human pathologies

MT Maung, A Carlson, M Olea‐Flores… - The FASEB …, 2021 - Wiley Online Library
Copper (Cu) is an essential micronutrient required for the activity of redox‐active enzymes
involved in critical metabolic reactions, signaling pathways, and biological functions …

[HTML][HTML] Organotin (IV) dithiocarbamate complexes: Chemistry and biological activity

JO Adeyemi, DC Onwudiwe - Molecules, 2018 - mdpi.com
Significant attention has been given to organotin (IV) dithiocabamate compounds in recent
times. This is due to their ability to stabilize specific stereochemistry in their complexes, and …

[HTML][HTML] Chemistry and some biological potential of bismuth and antimony dithiocarbamate complexes

JO Adeyemi, DC Onwudiwe - Molecules, 2020 - mdpi.com
Interest in the synthesis of Bi (III) and Sb (III) dithiocarbamate complexes is on the rise, and
this has been attributed to their wide structural diversity and their interesting application as …

The mechanisms of action involving dithiocarbamate complexes in biological systems

JO Adeyemi, DC Onwudiwe - Inorganica Chimica Acta, 2020 - Elsevier
The prevalence of infectious diseases, the generation of harmful products such as reactive
oxygen species (ROS) and free radicals within the human body system have created the …

Syntheses and characterization of novel antimony (III) and bismuth (III) derivatives containing β‐enamino ester along with antimicrobial evaluation, DFT calculation …

R Sangwan, S Beniwal, S Gaur… - … of Biochemical and …, 2024 - Wiley Online Library
Four novel antimony (III) and bismuth (III) complexes of the kind Cl–Sb–O–C (OR)–CH
(CH3) C–NH–(CH2) 2–NH–C (CH3) CH: C (OR)–O [where R=‐CH3, M= Sb (1a); R=–C2H5 …

Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress

TJ Hagele, JN Mazerik, A Gregory… - … journal of toxicology, 2007 - journals.sagepub.com
Currently, mercury has been identified as a risk factor of cardiovascular diseases among
humans. Here, the authors tested the hypothesis that mercury modulates the activity of the …

Phospholipase A2 Activation Regulates Cytotoxicity of Methylmercury in Vascular Endothelial Cells

JN Mazerik, T Hagele, S Sherwani… - … journal of toxicology, 2007 - journals.sagepub.com
Mercury has been identified as a risk factor for cardiovascular disease among humans.
Through diet, mainly fish consumption, humans are exposed to methylmercury, the …

[HTML][HTML] Why the NIH Trial to Assess Chelation Therapy (TACT) should be abandoned

KC Atwood IV, E Woeckner, RS Baratz… - The Medscape Journal …, 2008 - ncbi.nlm.nih.gov
Abstract The National Institutes of Health (NIH) Trial to Assess Chelation Therapy (TACT)
was begun in 2003 and is expected to be completed in 2009. It is a trial of office-based …

Mercury Activates Phospholipase A2 and Induces Formation of Arachidonic Acid Metabolites in Vascular Endothelial Cells

JN Mazerik, H Mikkilineni, VA Kuppusamy… - Toxicology …, 2007 - Taylor & Francis
Currently, mercury has been identified as a risk factor in cardiovascular diseases among
humans. Here, we tested our hypothesis that mercury modulates the activity of the vascular …

Modulation of vasodilator response via the nitric oxide pathway after acute methyl mercury chloride exposure in rats

S Omanwar, B Saidullah, K Ravi… - BioMed research …, 2013 - Wiley Online Library
Mercury exposure induces endothelial dysfunction leading to loss of endothelium‐
dependent vasorelaxation due to decreased nitric oxide (NO) bioavailability via increased …