[HTML][HTML] DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia

AK Dicke, A Pilatz, MJ Wyrwoll, M Punab… - Communications …, 2023 - nature.com
Non-obstructive azoospermia, the absence of sperm in the ejaculate due to disturbed
spermatogenesis, represents the most severe form of male infertility. De novo microdeletions …

Sperm retrieval rate and patient factors in azoospermia factor c microdeletion azoospermia: a systematic review

ZY Jiao, MR Li, L Zhuo, YY Fang, JY Pan… - BJU …, 2024 - Wiley Online Library
Objective To reveal the overall sperm retrieval rate (SRR) and range in patients with
azoospermia factor c (AZFc) microdeletion azoospermia by microdissection testicular sperm …

Elucidating the impact of Y chromosome microdeletions and altered gene expression on male fertility in assisted reproduction

N Pazoki, M Salehi, SA Angaji… - Human Molecular …, 2024 - academic.oup.com
Background Genetic abnormalities like Y chromosome microdeletions are implicated in
male infertility. This study investigated the association of azoospermia factor (AZF) region …

[HTML][HTML] Detection of AZF microdeletions and analysis of reproductive hormonal profiles in Hainan men undergoing assisted reproductive technology

Q He, Y Zhang, M Song, Y Zhou, D Lin, Y Ma, F Sun… - BMC urology, 2024 - Springer
Background Male infertility has become a global health problem, and genetic factors are one
of the essential causes. Y chromosome microdeletion is the leading genetic factor cause of …

In silico exploration and molecular dynamics of deleterious SNPs on the human TERF1 protein triggering male infertility

H Harmak, S Redouane, H Charoute… - Journal of …, 2023 - Taylor & Francis
By limiting chromosome erosion and end-to-end fusions, telomere integrity is critical for
chromosome stability and cell survival. During mitotic cycles or due to environmental …

AZF microdeletion affects semen parameters, sex hormone levels, and chromosome karyotypes in infertile men in Xinjiang

N Han, X Liu - Cellular and Molecular Biology, 2023 - mail.cellmolbiol.org
This study aimed to analyze the correlation between the microdeletion of different regions of
the azoospermia factor (AZF) gene and semen parameters, sex hormone levels, and …

Chromosomal abnormalities and Y chromosome microdeletions in patients with azoospermia and cryptozoospermia

PC Kong - Tạp chí Phụ sản, 2024 - vjog.vn
Purpose: To identify genetic abnormalities in patients with azoospermia and
cryptozoospermia examined and treated at Da Nang Hospital for Women and Children …