Natural nutraceuticals, especially functional foods, their ma-jor bioactive components, formulation, and health benefits for disease prevention-An overview

CG Awuchi, COR Okpala - Journal of Food Bioactives, 2022 - isnff-jfb.com
Nutraceuticals play wide range of important roles, from health promotion, increasing life
expectancy, maintaining body cell integrity, to reducing the risks of many diseases. As …

Natural products targeting macroautophagy signaling in hepatocellular carcinoma therapy: Recent evidence and perspectives

Y Chen, X Tan, W Zhang, Y Li, X Deng… - Phytotherapy …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC), presently the second leading cause of global cancer‐
related mortality, continues to pose significant challenges in the realm of medical oncology …

An Endogenous H2S-Activated Nanoplatform for Triple Synergistic Therapy of Colorectal Cancer

J Chen, F Xue, W Du, H Yu, Z Yang, Q Du, H Chen - Nano Letters, 2022 - ACS Publications
Overproduced hydrogen sulfide (H2S) is a highly potential target for precise colorectal
cancer (CRC) therapy; herein, a novel 5-Fu/Cur-P@ HMPB nanomedicine is developed by …

Natural compounds modulating mitophagy: Implications for cancer therapy

M Cao, Y Tang, Y Luo, F Gu, Y Zhu, X Liu, C Yan, W Hu… - Cancer Letters, 2023 - Elsevier
Cancer is considered as the second leading cause of mortality, and cancer incidence is still
growing rapidly worldwide, which poses an increasing global health burden. Although …

[HTML][HTML] Adipokines as regulators of autophagy in obesity-linked cancer

A García-Miranda, A Garcia-Hernandez… - Cells, 2022 - mdpi.com
Excess body weight and obesity have become significant risk factors for cancer
development. During obesity, adipose tissue alters its biological function, deregulating the …

[HTML][HTML] Green tea epigallocatechin-3-gallate regulates autophagy in male and female reproductive cancer

SW Hung, Y Li, X Chen, KO Chu, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
With a rich abundance of natural polyphenols, green tea has become one of the most
popular and healthiest nonalcoholic beverages being consumed worldwide …

Liposome encapsulated anticancer drugs on autophagy in cancer cells–current and future perspective

N Bhagya, KR Chandrashekar - International Journal of Pharmaceutics, 2023 - Elsevier
Autophagy act as a double-edged sword in cancer with both tumor promoting and inhibiting
roles. Under normal conditions of autophagy, the damaged cell organelles and other debris …

[HTML][HTML] Autophagy and cancer: Can tetrandrine be a potent anticancer drug in the near future?

N Bhagya, KR Chandrashekar - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Autophagy is an essential catabolic process in mammalian cells to maintain cellular integrity
and viability by degrading the old and damaged cell organelles and other contents with the …

[HTML][HTML] Mechanistic insights into fasting-induced autophagy in the aging heart

H Parvaresh, K Paczek, MAA Al-Bari… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Autophagy is a prosurvival mechanism for the clearance of accumulated abnormal proteins,
damaged organelles, and excessive lipids within mammalian cells. A growing body of data …

[HTML][HTML] Urolithin A targets the AKT/WNK1 axis to induce autophagy and exert anti-tumor effects in cholangiocarcinoma

H Sahashi, A Kato, M Yoshida, K Hayashi… - Frontiers in …, 2022 - frontiersin.org
Urolithin A (UA; 3, 8-dihydroxybenzo [c] chromen-6-one), a metabolite generated by
intestinal bacteria during the biotransformation of ellagitannins, has gained considerable …