Ginsenosides from American ginseng: chemical and pharmacological diversity

LW Qi, CZ Wang, CS Yuan - Phytochemistry, 2011 - Elsevier
Ginseng occupies a prominent position in the list of best-selling natural products in the
world. Compared to the long history of use and widespread research on Asian ginseng, the …

Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action

SA Nag, JJ Qin, W Wang, MH Wang, H Wang… - Frontiers in …, 2012 - frontiersin.org
Conventional chemotherapeutic agents are often toxic not only to tumor cells but also to
normal cells, limiting their therapeutic use in the clinic. Novel natural product anticancer …

Isolation and analysis of ginseng: advances and challenges

LW Qi, CZ Wang, CS Yuan - Natural product reports, 2011 - pubs.rsc.org
Covering: January 2000 to September 2010 Ginseng occupies a prominent position in the
list of best-selling natural products in the world. Because of its complex constituents …

American ginseng: potential structure–function relationship in cancer chemoprevention

LW Qi, CZ Wang, CS Yuan - Biochemical pharmacology, 2010 - Elsevier
Ginseng has a prominent position on the list of best-selling herbal products in the world, and
its main active constituents are thought to be ginsenosides. Compared with the long history …

[HTML][HTML] Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plants

L Yang, C Yang, C Li, Q Zhao, L Liu, X Fang, XY Chen - Science bulletin, 2016 - Elsevier
Plants synthesize and accumulate large amount of specialized (or secondary) metabolites
also known as natural products, which provide a rich source for modern pharmacy. In China …

[HTML][HTML] Comparative phenolic compound profiles and antioxidative activity of the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) according to …

IM Chung, JJ Lim, MS Ahn, HN Jeong, TJ An… - Journal of ginseng …, 2016 - Elsevier
Background The study of phenolic compounds profiles and antioxidative activity in ginseng
fruit, leaves, and roots with respect to cultivation years, and has been little reported to date …

[HTML][HTML] Chemical and pharmacological studies of saponins with a focus on American ginseng

CS Yuan, CZ Wang, SM Wicks… - Journal of ginseng …, 2010 - ncbi.nlm.nih.gov
Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) are the two
most recognized ginseng botanicals. It is believed that the ginseng saponins called …

Comprehensive Profiling and Quantification of Ginsenosides in the Root, Stem, Leaf, and Berry of Panax ginseng by UPLC-QTOF/MS

JW Lee, BR Choi, YC Kim, DJ Choi, YS Lee, GS Kim… - Molecules, 2017 - mdpi.com
The effective production and usage of ginsenosides, given their distinct pharmacological
effects, are receiving increasing amounts of attention. As the ginsenosides content differs in …

Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ss-catenin signaling

BC He, JL Gao, X Luo, J Luo… - International …, 2011 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common and deadly malignancies in the world.
Most CRCs are initiated by aberrant activation of the Wnt/ß-catenin signaling pathway …

Comparative studies of the antiproliferative effects of ginseng polysaccharides on HT-29 human colon cancer cells

H Cheng, S Li, Y Fan, X Gao, M Hao, J Wang, X Zhang… - Medical oncology, 2011 - Springer
Ginseng polysaccharide has anticancer activity. However, the structure–activity relationship
and the activity mechanism are still unclear. Therefore, it is necessary to study the anticancer …