BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to
bisphenol A (BPA). Moreover, BPA structural analogues (eg BPS, BPF, BPAF), used as BPA …

Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

The gonadotropin-releasing hormone (GnRH) neuronal network generates pulse and surge
modes of gonadotropin secretion critical for puberty and fertility. The arcuate nucleus …

The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

The gonadotropin-releasing hormone (GnRH) pulse is fundamental for mammalian
reproduction: GnRH pulse regimens are needed as therapies for infertile women as …

Genome-wide association studies (GWAS) have been used to study the genetic basis of a
wide variety of complex diseases and other traits. We describe UK Biobank GWAS results for …

The pulsatile release of GnRH and LH secretion is essential for fertility in all mammals.
Pulses of LH occur approximately every hour in follicular-phase females and every 2 to 3 …

Context Male infertility is defined as the inability to conceive following 1 year of regular
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …