Domino synthesis of thiazolo-fused six-and seven-membered nitrogen heterocycles via intramolecular heteroannulation of in-situ-generated 2-(het) aryl-4-amino-5 …

Y Kumar, H Ila - The Journal of Organic Chemistry, 2022 - ACS Publications
Synthesis of novel 2-(het) aryl-substituted thiazolo-fused six-and seven-membered
heterocycles, such as thiazolo [4, 5-b] pyridin-5 (4 H)-ones, thiazolo [4, 5-c] isoquinolin-5 (4 …

[HTML][HTML] An insight into symmetrical cyanine dyes as promising selective antiproliferative agents in Caco-2 colorectal cancer cells

JL Serrano, A Maia, AO Santos, E Lima, LV Reis… - Molecules, 2022 - mdpi.com
Cancer remains one of the diseases with the highest worldwide incidence. Several cytotoxic
approaches have been used over the years to overcome this public health threat, such as …

Novel asymmetric monomethine cyanine dyes derived from sulfobetaine benzothiazolium moiety as potential fluorescent dyes for non-covalent labeling of DNA

A Kurutos, O Ryzhova, V Trusova, U Tarabara… - Dyes and …, 2016 - Elsevier
Four novel monomethine cyanine dyes derived from a condensation reaction between N-
quaternary 2-thiomethylbenzothiazolic, and 4-methylquinolinuim choromophores have been …

Non-cytotoxic photostable monomethine cyanine platforms: Combined paradigm of nucleic acid staining and in vivo imaging

A Kurutos, T Ilic-Tomic, FS Kamounah… - … of Photochemistry and …, 2020 - Elsevier
Cyanine based chemosensing platforms have successfully been employed over the past
couple of decades in various fields of biomolecular sciences. Still a substantial number of …

Probing the structural properties of DNA/RNA grooves with sterically restricted phosphonium dyes: screening of dye cytotoxicity and uptake

I Crnolatac, LM Tumir, NY Lesev, AA Vasilev… - …, 2013 - Wiley Online Library
To explore in greater detail the recently reported rare kinetic differentiation between homo‐
polymeric and alternating AT‐DNA sequences by using sterically restricted phosphonium …

Spectroscopic and molecular docking studies of the interactions of monomeric unsymmetrical polycationic fluorochromes with DNA and RNA

O Zhytniakivska, M Girych, V Trusova, G Gorbenko… - Dyes and …, 2020 - Elsevier
The photophysical properties of a series of unsymmetrical di-and tricationic monomethine
cyanine dyes were studied in the presence of nucleic acids using combined spectroscopic …

Synthesis, spectral properties of cell-permeant dimethine cyanine dyes and their application as fluorescent probes in living cell imaging and flow cytometry

XH Zhang, Q Liu, HJ Shi, LY Wang, YL Fu, XC Wei… - Dyes and …, 2014 - Elsevier
A series of dimethine cyanine dyes, used as fluorescent probes, were synthesized under
microwave irradiation, and identified by 1 H NMR, IR, elemental analysis and HRMS. The …

ZnCl2‐Promoted One‐Pot Three‐Component Synthesis of Multisubstituted Thiazolo[4,5‐b]pyridines and Thieno[2,3‐b:4,5‐b′]dipyridines

L Luo, L Meng, Y Peng, Y Xing, Q Sun… - European Journal of …, 2015 - Wiley Online Library
A ZnCl2‐promoted one‐pot synthesis of multisubstituted thiazolo [4, 5‐b] pyridines and
thieno [2, 3‐b: 4, 5‐b′] dipyridines from mercaptonitrile salts, α‐bromo ketones and ketones …

Synthesis, crystal structures, and spectral properties of double N-alkylated dimethine cyanine dyes and their interactions with biomolecules and living cells

H Jia, Y Lv, S Wang, D Sun, L Wang - RSC advances, 2015 - pubs.rsc.org
Six new double N-alkylated dimethine cyanine dyes were synthesized and the crystal
structures of two of the dyes were analyzed by X-ray diffraction. The investigation of the …

Simple Synthesis of Fused Thiazolo [4, 5-b] pyridines through Successive SNAr Processes

AM Starosotnikov, MA Bastrakov, VV Kachala… - Synlett, 2021 - thieme-connect.com
A convenient process is described for the synthesis of novel thiazolo [4, 5-b] pyridines fused
with triazole or pyrimidine rings. The base-promoted reactions of 2-chloro-3-nitropyridines …