The broad conceptualization of fertility preservation and restoration has become already a
major concern in the modern western world since a large number of individuals often face it …

The decline in fertility in aging women, especially those with poor ovarian response (POR)
or primary ovarian insufficiency (POI), is a major concern for modern IVF centers. Fertility …

STUDY QUESTION Does a chemically defined maturation medium supplemented with
FGF2, LIF, and IGF1 (FLI) improve in vitro maturation (IVM) of cumulus–oocyte complexes …

Cervical cancer is one of the leading causes of cancer-related death in women of
reproductive age. The established fertility-sparing approaches for the management of early …

Menopausal transition entails a progressive decrease in hormone production by the ovaries
that lead to important physical and psychological changes that could significantly affect …

Background Cancer treatments of the last decades improve the survival rate of children and
adolescents. However, chemo-and radiotherapy result in gonadal damage, leading to acute …

Fertility preservation (FP) in pediatric and adolescent oncology patients presents a complex
interplay between cancer treatment imperatives and reproductive aspirations, demanding a …

Objective The efficiency of ovarian tissue transplantation (OTT) was established in terms of
ovarian function recovery (95% of cases), number of live births (over 200 worldwide to date) …

Hereditary cancers mostly affect the adolescent and young adult population (AYA) at
reproductive age. Mutations in BReast CAncer (BRCA) genes are responsible for the …

While ovarian tissue cryopreservation (OTC) is an important fertility preservation option, it
has its limitations. Improving OTC and ovarian tissue transplantation (OTT) must include …