Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues

HC Probst, P Stoitzner, L Amon… - European Journal of …, 2023 - Wiley Online Library
This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …

Dendritic cells in asthma

MJ van Helden, BN Lambrecht - Current opinion in immunology, 2013 - Elsevier
Highlights•Dendritic cells (DCs) are essential for inducing Th2 immunity to several
allergens.•Similar to other organs, lung DCs are a heterogeneous population of …

[图书][B] Tuberculosis and the tubercle bacillus

WR Jacobs Jr, H McShane, V Mizrahi, IM Orme - 2020 - books.google.com
Can today's innovative practices and molecular tools tame this ancient disease? One third of
the world's population is infected with tuberculosis (TB), with about 10 million new cases …

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

J Novak, O Cerny, A Osickova, I Linhartova, J Masin… - Toxins, 2017 - mdpi.com
Bordetellae, pathogenic to mammals, produce an immunomodulatory adenylate cyclase
toxin–hemolysin (CyaA, ACT or AC-Hly) that enables them to overcome the innate immune …

Innate immune cell suppression and the link with secondary lung bacterial pneumonia

DJ Morgan, J Casulli, C Chew, E Connolly… - Frontiers in …, 2018 - frontiersin.org
Secondary infections arise as a consequence of previous or concurrent conditions and
occur in the community or in the hospital setting. The events allowing secondary infections to …

Respiratory mononuclear phagocytes in human influenza A virus infection: their role in immune protection and as targets of the virus

S Vangeti, M Yu, A Smed-Sörensen - Frontiers in immunology, 2018 - frontiersin.org
Emerging viruses have become increasingly important with recurrent epidemics. Influenza A
virus (IAV), a respiratory virus displaying continuous re-emergence, contributes significantly …

The diversity of myeloid immune cells shaping wound repair and fibrosis in the lung

L Florez‐Sampedro, S Song, BN Melgert - Regeneration, 2018 - Wiley Online Library
In healthy circumstances the immune system coordinates tissue repair responses in a tight
balance that entails efficient inflammation for removal of potential threats, proper wound …

Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function

K Bomb, L Pradhan, Q Zhang, BM Jarai… - Biomaterials …, 2022 - pubs.rsc.org
The pulmonary fibrotic microenvironment is characterized by increased stiffness of lung
tissue and enhanced secretion of profibrotic soluble cues contributing to a feedback loop …

Innate immune responses to tuberculosis

JS Schorey, LS Schlesinger - Microbiology spectrum, 2016 - Am Soc Microbiol
Tuberculosis remains one of the greatest threats to human health. The causative bacterium,
Mycobacterium tuberculosis, is acquired by the respiratory route. It is exquisitely adapted to …

Bio-inspired materials in drug delivery: Exploring the role of pulmonary surfactant in siRNA inhalation therapy

L De Backer, A Cerrada, J Pérez-Gil… - Journal of Controlled …, 2015 - Elsevier
Many pathologies of the respiratory tract are inadequately treated with existing small
molecule-based therapies. The emergence of RNA interference (RNAi) enables the post …