Sodium‐Glucose Cotransporter‐2 Inhibitors After Acute Myocardial Infarction in Patients With Type 2 Diabetes: A Population‐Based Investigation

O Kwon, JP Myong, Y Lee, YJ Choi, JE Yi… - Journal of the …, 2023 - Am Heart Assoc
Background Whether the early use of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors
have cardioprotective effects following acute myocardial infarction is unknown. Thus, we …

Declining risk of heart failure hospitalization following first acute myocardial infarction in Scotland between 1991–2016

KF Docherty, AM Jackson, M Macartney… - European Journal of …, 2023 - Wiley Online Library
Aim Mortality from acute myocardial infarction (AMI) has declined, increasing the pool of
survivors at risk of later development of heart failure (HF). However, coronary reperfusion …

Dapagliflozin in patients with heart failure and previous myocardial infarction: A participant‐level pooled analysis of DAPA‐HF and DELIVER

A Peikert, M Vaduganathan, BL Claggett… - European Journal of …, 2024 - Wiley Online Library
Aims Patients with heart failure (HF) and history of myocardial infarction (MI) face a higher
risk of disease progression and clinical events. Whether sodium–glucose cotransporter 2 …

[HTML][HTML] Sacubitril/valsartan attenuates myocardial inflammation, hypertrophy, and fibrosis in rats with heart failure with preserved ejection fraction

YJ Shi, CG Yang, WB Qiao, YC Liu, SY Liu… - European Journal of …, 2023 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) represents a multifaceted syndrome
related to complex pathologic mechanisms. Sacubitril/valsartan (Sac/val) has demonstrated …

Progress of Mitochondrial Function Regulation in Cardiac Regeneration

YX Chen, AR Zhao, TW Wei, H Wang… - Journal of Cardiovascular …, 2024 - Springer
Heart failure and myocardial infarction, global health concerns, stem from limited cardiac
regeneration post-injury. Myocardial infarction, typically caused by coronary artery blockage …

Pharmacological Modulation by Low Molecular Weight Heparin of Purinergic Signaling in Cardiac Cells Prevents Arrhythmia and Lethality Induced by Myocardial …

CEB Filho, AHP Barbosa, LAD Nicolau… - Journal of …, 2023 - mdpi.com
Background: Although several studies suggest that heparins prevent arrhythmias caused by
acute myocardial infarction (AMI), the molecular mechanisms involved remain unclear. To …

Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3 …

ZY Zhang, ZH Yang, S Wang, SL Feng, XL Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Optimized New Shengmai Powder (ONSMP) is a
sophisticated traditional Chinese medicinal formula renowned for bolstering vital energy …

SGLT2 Inhibitors Squeak Out a Win in Patients Post-MI

JA Udell - NEJM evidence, 2024 - evidence.nejm.org
James et al1 report the results of the DAPA-MI (DAPAagliflozin in patients without diabetes
mellitus with acute Myocardial Infarction) trial, which studied the efficacy and safety of early …

Outcomes in Patients with Acute Myocardial Infarction and Known Sleep Apnea: A Nationwide Analysis

C Rabec, C Sombrun, SA Bentounes… - Journal of Clinical …, 2023 - mdpi.com
Background. Sleep apnea (SA) is a common breathing disorder characterized by repetitive
upper airway narrowing and closure. Although SA has been demonstrated to be an …

Sacubitril/valsartan compared to ramipril in high‐risk post‐myocardial infarction patients stratified according to use of mineralocorticoid receptor antagonists: Insight …

M Schou, B Claggett, ZM Miao… - European Journal of …, 2024 - Wiley Online Library
Aim It is unknown whether safety and clinical endpoints by use of sacubitril/valsartan (an
angiotensin receptor–neprilysin inhibitor [ARNI]) are affected by mineralocorticoid receptor …