Peptide science: A “rule model” for new generations of peptidomimetics

HR Reese, CC Shanahan, C Proulx, S Menegatti - Acta biomaterialia, 2020 - Elsevier
Peptides have been heavily investigated for their biocompatible and bioactive properties.
Though a wide array of functionalities can be introduced by varying the amino acid …

[HTML][HTML] Lysates of a Probiotic, Lactobacillus rhamnosus, Can Improve Skin Barrier Function in a Reconstructed Human Epidermis Model

YO Jung, H Jeong, Y Cho, EO Lee, HW Jang… - International journal of …, 2019 - mdpi.com
The main function of the skin is to protect the body from the external environment. The
barrier function of the skin is mainly provided by the stratum corneum, which consists of …

Layer-by-Layer Analysis of In Vitro Skin Models

E Footner, K Firipis, E Liu, C Baker… - ACS Biomaterials …, 2023 - ACS Publications
In vitro human skin models are evolving into versatile platforms for the study of skin biology
and disorders. These models have many potential applications in the fields of drug testing …

Baicalein inhibits matrix metalloproteinase 1 expression via activation of TRPV 1‐Ca‐ERK pathway in ultraviolet B–irradiated human dermal fibroblasts

KF Huang, KH Ma, YJ Chang, LC Lo… - Experimental …, 2019 - Wiley Online Library
Abstract Increased matrix metalloproteinase 1 (MMP‐1) expression is a feature of photo‐
aged skin. We investigated the effects of baicalein and sulphoraphane on ultraviolet B (UVB) …

Electric currents of 448 kHz upregulate anti‐senescence pathways in human dermal fibroblasts

E Toledano‐Macías… - Journal of Cosmetic …, 2024 - Wiley Online Library
Background Currently, finding new therapeutic strategies that reduce skin aging is a
challenge for dermatologists and aesthetic doctors. In recent years, physical therapies have …

[HTML][HTML] Fasiglifam (TAK-875), a G protein-coupled receptor 40 (GPR40) agonist, may induce hepatotoxicity through reactive oxygen species generation in a GPR40 …

MJ Kim, GJ Gu, YS Koh, SH Lee, YR Na… - Biomolecules & …, 2018 - ncbi.nlm.nih.gov
Abstract Fasiglifam (TAK-875) a G-protein coupled receptor 40 (GPR40) agonist,
significantly improves hyperglycemia without hypoglycemia and weight gain, the major side …

Withania somnifera root extract inhibits MGO-induced skin fibroblast cells dysfunction via ECM-integrin interaction

X Liu, C Chen, Y Lin, Y Liu, S Cai, D Li, L Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Withania somnifera (L.) Dunal, known as Ashwagandha,
has long been used in traditional medicine in Ayurveda, India, a representative adaptogen …

Human skin explants an in vitro approach for assessing UVB induced damage

C Khalil - Toxicology in Vitro, 2018 - Elsevier
Lifestyle changes involving frequent outdoor activities are contributing to higher exposure to
harmful ultraviolet light (UVB). The acute effects of UVB irradiation on human skin was …

[HTML][HTML] Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng (CA Mey.) Adventitious Root

KS Lee, S Lee, H Wang, G Lee, S Kim, YH Ryu… - Molecules, 2023 - mdpi.com
Polydeoxyribonucleotide (PDRN) has the ability to regenerate skin cells and improve the
skin barrier and wound healing. This study investigated the possibility of replacing animal …

[HTML][HTML] CO2 lattice laser reverses skin aging caused by UVB

H Wang, B Guo, Q Hui, F Lin, K Tao - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
The carbon dioxide (CO 2) lattice laser has been successfully used to treat facial skin
photoaging induced by UV light. In this study, we analyzed the effect of CO 2 lattice laser …