Background Esophageal cancer (EC) is a frequently occurring cancer with poor prognosis
despite combined therapeutic strategies. Many biomarkers have been proposed as …

Background: VEGF is a prime mediator of tumorigenesis and metastasis. Various studies
assessing the prognostic value of VEGF in patients with esophageal cancer remain …

Abstract Background Cyclooxygenase-2 (COX-2) has recently been considered to promote
lymphangiogenesis by up-regulating vascular endothelial growth factor-C (VEGF-C) in …

Abstract Background/Aims We combined two different signal pathways on transforming
growth factor β1 (TGF-β1)-Smad and vascular endothelial growth factor C (VEGF-C)/VEGF …

Diphyllin is a natural component of traditional Chinese medicine, which effectively inhibits V-
ATPase activity and affects the progression of cancer. However, few studies have been …

Background Esophageal squamous cell carcinoma (ESCC) is the most common histologic
subtype of esophageal cancer globally. The development of squamous cell carcinoma has …

The objective is to explore the expression of high mobility group box 1 (HMGB1) in
esophageal squamous cell carcinoma (ESCC) and its relationship with lymph node …

BACKGROUND: The prognostic value of vascular endothelial growth factor C (VEGF-C) in
patients with esophageal cancer (EC) remains controversial. The aim of this meta-analysis …

Esophageal cancer is an aggressive human malignancy with increasing incidence in the
developed world. VEGF-C makes crucial contributions to esophageal cancer progression …

Purpose: The purpose of this study was to comprehensively and quantitatively review
eligible published studies to explore the prognostic significance of vascular endothelial …