Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?

MB Boffa, ML Koschinsky - Journal of lipid research, 2016 - ASBMB
Elevated plasma concentrations of lipoprotein (a)[Lp (a)] have been determined to be a
causal risk factor for coronary heart disease, and may similarly play a role in other …

Emerging views of statin pleiotropy and cholesterol lowering

D Yu, JK Liao - Cardiovascular Research, 2022 - academic.oup.com
Over the past four decades, no class of drugs has had more impact on cardiovascular health
than the 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors or statins. Developed as …

High-density lipoprotein as a modulator of platelet and coagulation responses

M van der Stoep, SJA Korporaal… - Cardiovascular …, 2014 - academic.oup.com
Platelets and coagulation factors are involved in the process of haemostasis, which ensures
undisturbed blood flow upon vessel wall damage. However, excessive platelet aggregation …

The effect of PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibition on the risk of venous thromboembolism

NA Marston, Y Gurmu, GEM Melloni, M Bonaca… - Circulation, 2020 - Am Heart Assoc
Background: The relationship between cholesterol levels and risk of venous
thromboembolism (VTE) is uncertain. We set out to determine the effect of PCSK9 …

[HTML][HTML] Oxidized low‐density lipoprotein in inflammation‐driven thrombosis

G Obermayer, T Afonyushkin, CJ Binder - Journal of Thrombosis and …, 2018 - Elsevier
Thrombosis is the defining feature of the most prevalent causes of cardiovascular mortality,
such as myocardial infarction, stroke, and pulmonary artery embolism. Although platelet …

Venous thromboembolism has the same risk factors as atherosclerosis: A PRISMA-compliant systemic review and meta-analysis

Y Mi, S Yan, Y Lu, Y Liang, C Li - Medicine, 2016 - journals.lww.com
Background: Previous studies have shown that idiopathic pulmonary embolism is positively
associated with other cardiovascular events, such as myocardial infarction and stroke …

Thrombosis in central obesity and metabolic syndrome: mechanisms and epidemiology

PE Morange, MC Alessi - Thrombosis and haemostasis, 2013 - thieme-connect.com
Central obesity is a key feature of the metabolic syndrome (metS), a multiplex risk factor for
subsequent development of type 2 diabetes and cardiovascular disease. Many metabolic …

Association between blood lipid levels and lower extremity deep venous thrombosis: a population-based cohort study

Y Huang, H Ge, X Wang… - Clinical and Applied …, 2022 - journals.sagepub.com
Objects To investigate the potential clinical significance between blood lipid levels and
lower extremity deep venous thrombosis (LEDVT). Methods: This cohort study included 500 …

A bidirectional Mendelian randomized study of classical blood lipids and venous thrombosis

L Lin, P Luo, M Yang, J Wang, W Hou, P Xu - Scientific Reports, 2023 - nature.com
There is still some controversy about the relationship between lipids and venous thrombosis
(VTE). A bidirectional Mendelian randomization (MR) study was conducted to clarify the …

[HTML][HTML] Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia

D Bhojwani, R Darbandi, D Pei, LB Ramsey… - European journal of …, 2014 - Elsevier
Background Asparaginase and steroids can cause hypertriglyceridaemia in children with
acute lymphoblastic leukaemia (ALL). There are no guidelines for screening or management …