Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Importance Approximately 20% to 30% of patients admitted to an intensive care unit have
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …

During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue
oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has …

Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities
caused by a dysregulated host response to infection. Sepsis progression into septic shock is …

• Diagnosing sepsis in older adults is difficult, with organ dysfunction often reflecting
comorbidities rather than a dysregulated response to infection• The term sepsis should not …

Abstract The Centers for Medicare & Medicaid Services (CMS) introduced the Severe
Sepsis/Septic Shock Management Bundle (SEP-1) as a pay-for-reporting measure in 2015 …

Septic shock is a common condition associated with hypotension and organ dysfunction. It is
associated with high mortality rates of up to 60% despite the best recommended …

The impact of left ventricular (LV) diastolic dysfunction (DD) on the outcome of patients with
heart failure was established over three decades ago. Nevertheless, the relevance of LVDD …

Sepsis causes significant morbidity and mortality worldwide. Resuscitation is a cornerstone
of management. This review covers five areas of evolving practice in the management of …

Study objective To evaluate the impact of a dynamic arterial elastance guided
norepinephrine weaning strategy on the occurrence of acute kidney injury (AKI) in patients …