To develop a systems biology model of fibrosis progression within the human lung we
performed RNA sequencing and microRNA analysis on 95 samples obtained from 10 …

Introduction Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic
liver disease worldwide and closely interconnected to the metabolic syndrome. Liver …

This is a time of substantial progress in the evaluation and care of patients with idiopathic
pulmonary fibrosis (IPF). In addition to the approval and widespread availability of the first …

Mitochondria regulate not only cell functions through energy generation but also aging-
associated cell phenotypes. Impaired mitochondrial structural and functional integrity …

Alveolar epithelial type 2 cell (AEC2) dysfunction is implicated in the pathogenesis of adult
and pediatric interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF); …

Idiopathic pulmonary fibrosis (IPF) is a progressive fatal interstitial lung disease without an
effective cure. Herein, we explore the role of 3, 5, 3′-triiodothyronine (T3) administration on …

The heterogeneity of idiopathic pulmonary fibrosis (IPF) limits its diagnosis and treatment.
The association between the pathophysiological features and the serum protein signatures …

Abstract Background Vitamin D (VitD) is a steroid hormone with cytoprotective and anti-
inflammatory properties. Epidemiological studies have suggested a link between VitD …

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with limited therapeutic
options. Current evidence suggests that IPF may be initiated by repeated epithelial injuries …

The use of exogenous mitochondria to replenish damaged mitochondria has been proposed
as a strategy for the treatment of pulmonary fibrosis. However, the success of this strategy is …