Abstract The Thyroid Hormone (TH) activating enzyme, type 2 Deiodinase (D2), is
functionally required to elevate the TH concentration during cancer progression to advanced …

Background: Illness severity in patients infected with COVID-19 is variable. Methods: Here,
we conducted an observational, longitudinal, and prospective cohort study to investigate …

Mitochondria are essential organelles for cell metabolism, growth, and function.
Mitochondria in lung cells have important roles in regulating surfactant production …

Pulmonary fibrosis arises from the repeated epithelial mild injuries and insufficient repair
lead to over activation of fibroblasts and excessive deposition of extracellular matrix, which …

Idiopathic pulmonary fibrosis (IPF) is one of many clinical syndromes that are associated
with aging, and is increasing in both incidence and prevalence with the rapid rise in aging …

Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic
pulmonary fibrosis (IPF), inhalational, environmental, or occupational exposures in …

Idiopathic pulmonary fibrosis (IPF) is a fatal ageing-related disease linked to mitochondrial
dysfunction. The present study aimed to determine whether peroxisome proliferator …

In healthy kidneys, interstitial fibroblasts are responsible for the maintenance of renal
architecture. Progressive interstitial fibrosis is thought to be a common pathway for chronic …

Context Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with type 2
diabetes mellitus (T2DM) and associated with significant morbidity and mortality. Thyroid …

Significance: Idiopathic pulmonary fibrosis (IPF) is a progressive age-related lung disease
with a median survival of only 3 years after diagnosis. The pathogenic mechanisms behind …