Evaluating medical device and material thrombosis under flow: current and emerging technologies

JK Hong, L Gao, J Singh, T Goh, AM Ruhoff… - Biomaterials …, 2020 - pubs.rsc.org
Although blood-contacting medical devices are used widely, blood clot formation
(thrombosis) leads to device failure and potentially catastrophic adverse thrombotic events …

[HTML][HTML] Challenge of material haemocompatibility for microfluidic blood-contacting applications

G Newman, A Leclerc, W Arditi… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Biological applications of microfluidics technology is beginning to expand beyond the
original focus of diagnostics, analytics and organ-on-chip devices. There is a growing …

[HTML][HTML] Monolithic polymeric porous superhydrophobic material with pneumatic plastron stabilization for functionally durable drag reduction in blood-contacting …

J Marlena, JKS Tan, Z Lin, DX Li, B Zhao, HL Leo… - NPG Asia …, 2021 - nature.com
Superhydrophobic (SHP) surfaces can provide substantial reductions in flow drag forces
and reduce blood damage in cardiovascular medical devices. However, strategies for …

Continuous LVAD monitoring reveals high suction rates in clinically stable outpatients

C Gross, H Schima, T Schlöglhofer, K Dimitrov… - Artificial …, 2020 - Wiley Online Library
Suction of the left ventricle can lead to potentially life‐threatening events in left ventricular
assist device (LVAD) patients. With the resolution of currently available clinical LVAD …

Hemolysis associated with Impella heart pump positioning: In vitro hemolysis testing and computational fluid dynamics modeling

N Roberts, U Chandrasekaran, S Das… - … journal of artificial …, 2020 - journals.sagepub.com
Introduction: Short-term mechanical circulatory support devices provide temporary
hemodynamic support in heart failure and are increasingly used to enable recovery or as a …

Acquired platelet defects are responsible for nonsurgical bleeding in left ventricular assist device recipients

K Arias, W Sun, S Wang, EN Sorensen, E Feller… - Artificial …, 2022 - Wiley Online Library
Background Left ventricular assist devices (LVADs) have been used as a standard treatment
option for patients with advanced heart failure. However, these devices are prone to adverse …

Two-dimensional modeling and system identification of the laser metal deposition process

PM Sammons, DA Bristow… - Journal of …, 2019 - asmedigitalcollection.asme.org
Additive manufacturing (AM) processes fabricate parts by adding material in a layer-by-layer
fashion. In order to enable closed-loop process control—a major hurdle in the adoption of …

[HTML][HTML] Low-level light therapy protects red blood cells against oxidative stress and hemolysis during extracorporeal circulation

T Walski, A Drohomirecka, J Bujok, A Czerski… - Frontiers in …, 2018 - frontiersin.org
Aim: An activation of non-specific inflammatory response, coagulation disorder, and blood
morphotic elements damage are the main side effects of the extracorporeal circulation …

The chemical and laboratory investigation of hemolysis

AJ Siddon, CA Tormey - Advances in Clinical Chemistry, 2019 - Elsevier
The abnormal breakdown of circulating red blood cells (RBCs), also known as hemolysis, is
a significant clinical issue that can present as a primary disorder or arise secondary to …

Mesh sensitivity analysis for quantitative shear stress assessment in blood pumps using computational fluid dynamics

S Gross-Hardt, F Boehning… - Journal of …, 2019 - asmedigitalcollection.asme.org
The reduction of excessive, nonphysiologic shear stresses leading to blood trauma can be
the key to overcome many of the associated complications in blood recirculating devices. In …