Phenylpropanoid metabolism is one of the most important metabolisms in plants, yielding
more than 8,000 metabolites contributing to plant development and plant–environment …

During their evolution, plants have acquired the ability to produce a huge variety of
compounds. Unlike the specialized metabolites that accumulate in limited numbers of …

Flavones are a class of flavonoids that are a subject of increasing interest because of their
biological activities in vitro and in vivo. This article reviews the major sources of flavones and …

Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …

Phenylpropanoids are a large class of plant secondary metabolites derived from aromatic
amino acids phenylalanine in most plants or tyrosine in partial monocots. It mainly includes …

Isoflavonoids, which include a variety of secondary metabolites, are derived from the
phenylpropanoid pathway and are distributed predominantly in leguminous plants. These …

Abstract Scutellaria baicalensis Georgi, or Chinese skullcap, has been widely used as a
medicinal plant in China for thousands of years, where the preparation from its roots is …

With the climate constantly changing, plants suffer more frequently from various abiotic and
biotic stresses. However, they have evolved biosynthetic machinery to survive in stressful …

Citrus fruit and juices represent one of the main sources of compounds with a high potential
for health promoting properties. Among these compounds, flavanones (such as hesperetin …

The biosynthesis of natural products often requires eukaryotic cytochrome P450s (P450s) in
combination with P450 reductase, in physical proximity, to perform electron-transfer …