Past and present progress in the pharmacologic treatment of schizophrenia

JM Kane, CU Correll - The Journal of clinical psychiatry, 2010 - psychiatrist.com
Despite treatment advances over the past decades, schizophrenia remains one of the most
severe psychiatric disorders that is associated with a chronic relapsing course and marked …

Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial

RR Wu, JP Zhao, H Jin, P Shao, MS Fang, XF Guo… - Jama, 2008 - jamanetwork.com
Context Weight gain, a common adverse effect of antipsychotic medications, is associated
with medical comorbidities in psychiatric patients. Objective To test the efficacy of lifestyle …

Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challenges

WW Fleischhacker, M Cetkovich-Bakmas… - Journal of Clinical …, 2008 - psychiatrist.com
Background: An increasing body of evidence suggests that, in comparison to the general
population, patients with severe mental illnesses such as schizophrenia or bipolar disorder …

BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment

SJ Cooper, GP Reynolds… - Journal of …, 2016 - journals.sagepub.com
Excess deaths from cardiovascular disease are a major contributor to the significant
reduction in life expectancy experienced by people with schizophrenia. Important risk factors …

[图书][B] Handbook of Obesity--Volume 1: Epidemiology, Etiology, and Physiopathology

GA Bray - 2014 - books.google.com
In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Atypical antipsychotics dose dependent? A literature review

V Simon, R Van Winkel, M De Hert - J Clin Psych, 2009 - legacy.psychiatrist.com
Background: Numerous publications have provided evidence for clinically important
metabolic adverse effects of antipsychotics, but there is no systematic evaluation as to …

Metabolic considerations in the use of antipsychotic medications: a review of recent evidence

MD Britton Ashley Arey - J Clin Psychiatry, 2007 - psychiatrist.com
Compared with the general population, persons with schizophrenia have up to a 20%
shorter lifespan, with cardiovascular disease as the leading cause of death. In addition …

Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication

MA De Hert, R van Winkel, D Van Eyck… - Schizophrenia …, 2006 - Elsevier
The presence of the metabolic syndrome is an important risk factor for cardiovascular
disease and diabetes. There are limited data on the prevalence of the metabolic syndrome …

Clozapine's multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms …

A de Bartolomeis, L Vellucci, A Barone… - Pharmacology & …, 2022 - Elsevier
Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …

A novel platform based on CoMn2O4-rGO/1-ethyl-3-methylimidazolium chloride modified carbon paste electrode for voltammetric detection of pethidine in the …

H Shahinfard, M Shabani-Nooshabadi, A Reisi-Vanani… - Chemosphere, 2022 - Elsevier
The present work focuses on the development of a new electrochemical platform based on
CoMn 2 O 4-rGO/1-ethyl-3-methylimidazolium chloride modified carbon paste electrode …