Cardiac side effects of psychiatric drugs

P Mackin - Human Psychopharmacology: Clinical and …, 2008 - Wiley Online Library
This review describes the common effects of psychotropic drugs on the cardiovascular
system and offers guidance for practical management. Selected reports from the literature …

Metabolic issues in patients affected by schizophrenia: clinical characteristics and medical management

A Ventriglio, A Gentile, E Stella, A Bellomo - Frontiers in neuroscience, 2015 - frontiersin.org
Patients affected by psychotic disorders are more likely to develop high rates of co-
morbidities, such as obesity, type 2 diabetes, dyslipidemias, hypertension, metabolic …

Metformin addition attenuates olanzapine-induced weight gain in drug-naive first-episode schizophrenia patients: a double-blind, placebo-controlled study

RR Wu, JP Zhao, XF Guo, YQ He… - American Journal of …, 2008 - Am Psychiatric Assoc
Objective: The purpose of this study was to assess the efficacy of metformin in preventing
olanzapine-induced weight gain. Method: Forty patients with schizophrenia were randomly …

Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder

R Van Winkel, M De Hert, D Van Eyck… - Bipolar …, 2008 - Wiley Online Library
Objectives: The presence of metabolic abnormalities is an important risk factor for
cardiovascular disease and diabetes. There are limited data on the prevalence of the …

The prevalence and mechanisms of metabolic syndrome in schizophrenia: a review

E Papanastasiou - Therapeutic advances in …, 2013 - journals.sagepub.com
Metabolic syndrome (MetS), a constellation of central obesity, hypertension, dyslipidaemia
and glucose intolerance, is highly prevalent in individuals with schizophrenia and conveys …

Metabolic monitoring for patients treated with antipsychotic medications

TA Cohn, MJ Sernyak - The Canadian Journal of Psychiatry, 2006 - journals.sagepub.com
Objectives: Metabolic side effects of antipsychotic treatment include weight gain,
dyslipidemia and increased susceptibility to diabetes. Patients with schizophrenia have …

Metabolic screening after the American Diabetes Association's consensus statement on antipsychotic drugs and diabetes

EH Morrato, JW Newcomer, S Kamat, O Baser… - Diabetes …, 2009 - Am Diabetes Assoc
OBJECTIVE Several second-generation antipsychotic (SGA) drugs have been associated
with weight gain, hyperglycemia, and dyslipidemia. We evaluated whether glucose and lipid …

Lack of insight in schizophrenia: impact on treatment adherence

PF Buckley, DA Wirshing, P Bhushan, JM Pierre… - CNS drugs, 2007 - Springer
People with schizophrenia commonly lack insight, that is, they are unaware of their illness
and the consequences thereof. One of the most important consequences of lack of insight is …

Potential mechanisms of atypical antipsychotic-induced metabolic derangement: clues for understanding obesity and novel drug design

R Coccurello, A Moles - Pharmacology & therapeutics, 2010 - Elsevier
Beside the therapeutic improvement over first-generation antipsychotics, the fact that
prescription of atypical agents is also associated to the emergence of severe metabolic …

Side effect burden of antipsychotic drugs in real life–Impact of gender and polypharmacy

TSJ Iversen, NE Steen, I Dieset, S Hope… - Progress in Neuro …, 2018 - Elsevier
Background Antipsychotic-associated side effects are well known and represent a significant
treatment challenge. Still, few large studies have investigated the overall side effect burden …