Revisiting the neurovascular unit
S Schaeffer, C Iadecola - Nature neuroscience, 2021 - nature.com
The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
F Leng, P Edison - Nature Reviews Neurology, 2021 - nature.com
Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
[HTML][HTML] Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale
The advent of neuroimaging has increased our understanding of brain function. While most
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …
[HTML][HTML] Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
Disclosures: D. Máthé reported grants from European Union H2020 HCEMM-739593 and
from NRDIO, Hungary, TKP-BIOImaging-2020-4.1. 1-TKP2020 during the conduct of the …
from NRDIO, Hungary, TKP-BIOImaging-2020-4.1. 1-TKP2020 during the conduct of the …
[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
[HTML][HTML] Pericyte control of blood flow across microvascular zones in the central nervous system
DA Hartmann, V Coelho-Santos… - Annual review of …, 2022 - annualreviews.org
The vast majority of the brain's vascular length is composed of capillaries, where our
understanding of blood flow control remains incomplete. This review synthesizes current …
understanding of blood flow control remains incomplete. This review synthesizes current …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease
C Iadecola - Neuron, 2017 - cell.com
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …
Review Group meeting of the National Institute of Neurological Disorders and Stroke …
The emerging nature of astrocyte diversity
BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …
homogeneous population tiling the entire central nervous system (CNS). However, this view …
Absorption, distribution, and toxicity of per-and polyfluoroalkyl substances (PFAS) in the brain: a review
Per-and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals colloquially
known as “forever chemicals” because of their high persistence. PFAS have been detected …
known as “forever chemicals” because of their high persistence. PFAS have been detected …