Cross-talk among oxytocin and arginine-vasopressin receptors: Relevance for basic and clinical studies of the brain and periphery

Z Song, HE Albers - Frontiers in neuroendocrinology, 2018 - Elsevier
Oxytocin (OT) and arginine-vasopressin (AVP) act in the brain to regulate social
cognition/social behavior and in the periphery to influence a variety of physiological …

The oxytocin–vasopressin pathway in the context of love and fear

CS Carter - Frontiers in endocrinology, 2017 - frontiersin.org
Vasopressin (VP) and oxytocin (OT) are distinct molecules; these peptides and their
receptors [OT receptor (OTR) and V1a receptor (V1aR)] also are evolved components of an …

[HTML][HTML] Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions

H Yu, W Miao, E Ji, S Huang, S Jin, X Zhu, MZ Liu… - Neuron, 2022 - cell.com
It is well known that affective and pleasant touch promotes individual well-being and
facilitates affiliative social communication, although the neural circuit that mediates this …

Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

KJ Parker, O Oztan, RA Libove… - Proceedings of the …, 2017 - National Acad Sciences
Autism spectrum disorder (ASD) is characterized by core social deficits. Prognosis is poor, in
part, because existing medications target only associated ASD features. Emerging evidence …

Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism

A Bertoni, F Schaller, R Tyzio, S Gaillard, F Santini… - Molecular …, 2021 - nature.com
Oxytocin is an important regulator of the social brain. In some animal models of autism,
notably in Magel2 tm1. 1Mus-deficient mice, peripheral administration of oxytocin in infancy …

Oxytocin in women's health and disease

N Liu, H Yang, L Han, M Ma - Frontiers in endocrinology, 2022 - frontiersin.org
Oxytocin (OT) is a nonapeptide mainly produced in the supraoptic and paraventricular
nuclei. OT in the brain and blood has extensive functions in both mental and physical …

Oxytocin and oxygen: the evolution of a solution to the 'stress of life'

CS Carter, MA Kingsbury - Philosophical Transactions of …, 2022 - royalsocietypublishing.org
Oxytocin (OT) and the OT receptor occupy essential roles in our current understanding of
mammalian evolution, survival, sociality and reproduction. This narrative review examines …

Roles of the oxytocin receptor (OXTR) in human diseases

K Pierzynowska, L Gaffke, M Żabińska, Z Cyske… - International journal of …, 2023 - mdpi.com
The oxytocin receptor (OXTR), encoded by the OXTR gene, is responsible for the signal
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …

Sex, love and oxytocin: Two metaphors and a molecule

CS Carter - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Dozens of studies, most conducted in the last four decades, have implicated oxytocin, as
well as vasopressin and their receptors, in processes that mediate selective sociality and the …

Imprinted genes and the manipulation of parenting in mammals

RM John, MJ Higgs, AR Isles - Nature Reviews Genetics, 2023 - nature.com
Genomic imprinting refers to the parent-of-origin expression of genes, which originates from
epigenetic events in the mammalian germ line. The evolution of imprinting may reflect a …