EBV-positive gastric cancer: current knowledge and future perspectives

K Sun, K Jia, H Lv, SQ Wang, Y Wu, H Lei… - Frontiers in …, 2020 - frontiersin.org
Gastric cancer is the fifth most common malignant tumor and second leading cause of
cancer-related deaths worldwide. With the improved understanding of gastric cancer, a …

Landscape of EBV-positive gastric cancer

M Saito, K Kono - Gastric Cancer, 2021 - Springer
Epstein–Barr virus-positive gastric cancer [EBV (+) GC] is associated with EBV infection and
is one of the GC subtypes defined by the Cancer Genome Atlas. EBV (+) GC has several …

MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia

K Katsaraki, P Karousi, PI Artemaki, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …

Epstein-Barr virus microRNAs in the pathogenesis of human cancers

BFR Caetano, BAS Jorge, BG Müller-Coan… - Cancer Letters, 2021 - Elsevier
Abstract The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with a variety of
human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In …

Viral encoded miRNAs in tumorigenesis: Theranostic opportunities in precision oncology

R Hull, R Marima, M Alaouna, D Demetriou, RM Reis… - Microorganisms, 2022 - mdpi.com
About 15% of all human cancers have a viral etiology. Although progress has been made,
understanding the viral oncogenesis and associated molecular mechanisms remain …

[HTML][HTML] Epstein-Barr virus deubiquitinating enzyme BPLF1 is involved in EBV carcinogenesis by affecting cellular genomic stability

H Wu, BW Han, T Liu, M Zhang, Y Wu, J Nie - Neoplasia, 2024 - Elsevier
Increased mutational burden and EBV load have been revealed from normal tissues to
Epstein-Barr virus (EBV)-associated gastric carcinomas (EBVaGCs). BPLF1, encoded by …

[HTML][HTML] The Emerging Role of Ferroptosis in EBV-Associated Cancer: Implications for Cancer Therapy

S He, C Luo, F Shi, J Zhou, L Shang - Biology, 2024 - mdpi.com
Simple Summary This review will discuss the connection between ferroptosis and Epstein–
Barr Virus as well as its associated cancers. It delves into both known and potential ways in …

Metabolic control by DNA tumor virus-encoded proteins

MA Prusinkiewicz, JS Mymryk - Pathogens, 2021 - mdpi.com
Viruses co-opt a multitude of host cell metabolic processes in order to meet the energy and
substrate requirements for successful viral replication. However, due to their limited coding …

Non-coding RNAs: Strategy for viruses' offensive

A Gallo, M Bulati, V Miceli, N Amodio, PG Conaldi - Non-coding RNA, 2020 - mdpi.com
The awareness of viruses as a constant threat for human public health is a matter of fact and
in this resides the need of understanding the mechanisms they use to trick the host. Viral …

MicroRNAs: Small but Key Players in Viral Infections and Immune Responses to Viral Pathogens

AN Bauer, N Majumdar, F Williams, S Rajput… - Biology, 2023 - mdpi.com
Simple Summary Viral outbreaks continue to be an obstacle to human health, with the
Severe Acute Respiratory Syndrome-related Coronavirus (SARS-CoV-2) pandemic …