Therapeutic potential of intermittent hypoxia: a matter of dose
A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …
triggers a bewildering array of both detrimental and beneficial effects in multiple …
Obstructive sleep apnea and the metabolic syndrome: the road to clinically-meaningful phenotyping, improved prognosis, and personalized treatment
J Gaines, AN Vgontzas, J Fernandez-Mendoza… - Sleep medicine …, 2018 - Elsevier
Obstructive sleep apnea (OSA) is an increasingly prevalent sleep disorder characterized by
upper airway obstruction during sleep, resulting in breathing pauses, intermittent hypoxia …
upper airway obstruction during sleep, resulting in breathing pauses, intermittent hypoxia …
Obstructive sleep apnoea and cardiovascular disease
M Sánchez-de-la-Torre… - The Lancet …, 2013 - thelancet.com
Obstructive sleep apnoea (OSA) is a common health concern caused by repeated episodes
of collapse of the upper airway during sleep. The events associated with OSA lead to brain …
of collapse of the upper airway during sleep. The events associated with OSA lead to brain …
[HTML][HTML] CPAP versus oxygen in obstructive sleep apnea
Background Obstructive sleep apnea is associated with hypertension, inflammation, and
increased cardiovascular risk. Continuous positive airway pressure (CPAP) reduces blood …
increased cardiovascular risk. Continuous positive airway pressure (CPAP) reduces blood …
Mechanisms of vascular damage in obstructive sleep apnea
M Kohler, JR Stradling - Nature Reviews Cardiology, 2010 - nature.com
Obstructive sleep apnea (OSA) is characterized by repetitive apnea–hypopnea cycles
during sleep, which are associated with oxygen desaturation and sleep disruption. Up to …
during sleep, which are associated with oxygen desaturation and sleep disruption. Up to …
Inflammation in sleep apnea: an update
Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular
disease (CVD). One theory to explain this relationship proposes that OSA can induce …
disease (CVD). One theory to explain this relationship proposes that OSA can induce …
Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised
as a major public health burden. Large-scale epidemiological studies have demonstrated an …
as a major public health burden. Large-scale epidemiological studies have demonstrated an …
Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial
M Kohler, AC Stoewhas, L Ayers, O Senn… - American journal of …, 2011 - atsjournals.org
Rationale: To establish a new approach to investigate the physiological effects of obstructive
sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous positive …
sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous positive …
Sleep, sleep-disordered breathing and metabolic consequences
Sleep profoundly affects metabolic pathways. In healthy subjects, experimental sleep
restriction caused insulin resistance (IR) and increased evening cortisol and sympathetic …
restriction caused insulin resistance (IR) and increased evening cortisol and sympathetic …
Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease
WT McNicholas - American journal of respiratory and critical care …, 2009 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome
represent two of the most prevalent chronic respiratory disorders in clinical practice, and …
represent two of the most prevalent chronic respiratory disorders in clinical practice, and …