Alpha lipoic acid improves endothelial function and oxidative stress in mice exposed to chronic intermittent hypoxia

M Badran, B Abuyassin, S Golbidi… - … medicine and cellular …, 2019 - Wiley Online Library
Objective. Obstructive sleep apnea (OSA) is characterized by recurrent airway collapse that
causes chronic intermittent hypoxia (CIH). OSA is associated with systemic inflammation and …

Sleep apnoea syndrome in 2011: current concepts and future directions

P Lévy, R Tamisier, C Minville… - European Respiratory …, 2011 - Eur Respiratory Soc
In the past two decades, obstructive sleep apnoea (OSA) has been identified as a common
clinical condition. Epidemiological studies have confirmed a high prevalence of the disease …

New frontiers in obstructive sleep apnoea

NT Ayas, AAJ Hirsch, I Laher, TD Bradley… - Clinical …, 2014 - portlandpress.com
OSA (obstructive sleep apnoea), the most common respiratory disorder of sleep, is caused
by the loss of upper airway dilating muscle activity during sleep superimposed on a narrow …

[HTML][HTML] Cardiovascular outcomes of continuous positive airway pressure therapy for obstructive sleep apnea

Y Peker, B Balcan - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Obstructive sleep apnea is a common disorder with increased risk for cardiovascular
morbidity and mortality. The first choice of treatment of obstructive sleep apnea is continuous …

Inflammatory processes and effects of continuous positive airway pressure (CPAP) in overlap syndrome

S Nural, E Günay, B Halici, S Celik, M Ünlü - Inflammation, 2013 - Springer
We aimed to compare serum levels of the inflammatory mediators including C-reactive
protein (CRP), tumor necrosis factor-α (TNF-α), and asymmetric dimethylarginine (ADMA) in …

Plasma pentraxin3 and arterial stiffness in men with obstructive sleep apnea

T Kasai, K Inoue, T Kumagai, M Kato… - American Journal of …, 2011 - academic.oup.com
Background Obstructive sleep apnea (OSA) induces inflammation and vascular damage that
might contribute to an increased risk of cardiovascular disease (CVD). However, the …

Cardiovascular aspects in obstructive sleep apnea syndrome–molecular issues, hypoxia and cytokine profiles

L Lavie, V Polotsky - Respiration, 2009 - karger.com
Obstructive sleep apnea syndrome (OSAS), which is a highly prevalent breathing disorder in
sleep, is an independent risk factor for cardiovascular morbidity and mortality. Results from …

The Sleep Apnea cardioVascular Endpoints (SAVE) Trial: rationale, ethics, design, and progress

NA Antic, E Heeley, CS Anderson, Y Luo, J Wang… - Sleep, 2015 - academic.oup.com
Abstract The Sleep Apnea cardioVascular Endpoints (SAVE) study is an ongoing
investigator-initiated and conducted, international, multicenter, open, blinded endpoint …

The effects of intermittent hypoxia on redox status, NF-κB activation, and plasma lipid levels are dependent on the lowest oxygen saturation

M Quintero, M del Carmen Gonzalez-Martin… - Free Radical Biology …, 2013 - Elsevier
Obstructive sleep apnea syndrome (OSAS) is described as repetitive obstructions of the
upper airways during sleep, causing concomitant episodes of systemic hypoxia and …

[HTML][HTML] Effects of CPAP-respiration on markers of glucose metabolism in patients with obstructive sleep apnoea syndrome: a systematic review and meta-analysis

L Hecht, R Möhler, G Meyer - GMS German Medical Science, 2011 - ncbi.nlm.nih.gov
Background: Obstructive Sleep Apnoea Syndrome (OSAS) is a condition of obstruction,
apneas and arousals while sleeping. It has been suggested that OSAS independently …