Chemoprevention is a relatively new and promising strategy to prevent human degenerative
diseases, including cancer, and is defined as the use of natural dietary compounds and/or …

Tetrahydrocurcumin (THC) is a metabolite of curcumin (CUR). It shares many of CUR's
beneficial biological activities in addition to being more water-soluble, chemically stable …

Inhibition of nitric oxide synthesis with N ω-nitro-l-arginine methyl ester (l-NAME) induces
marked hypertension and oxidative stress. Curcumin (CUR) has been shown strong …

Tetrahydrocurcumin (THC), a major metabolite of curcumin, possesses strong antioxidant
and cardioprotective properties. However, the activities of THC in hypertension and its …

Background: Beta-adrenergic blocking agents have been broadly used for treatment of
many cardiovascular diseases such as arterial hypertension and ischemic heart failure. Anti …

Abstract Aims Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR) differ in their
renin-angiotensin system function and sympathetic tone. The metabolism of angiotensins …

During cold acclimation, shivering is progressively replaced by nonshivering thermogenesis.
Brown adipose tissue (BAT) and skeletal muscle are relevant for nonshivering …

Background Propranolol, as a beta-adrenergic blocker is used for treatment of a large
number of cardiovascular diseases such as hypertension and arrhythmias. The inhibitory …

Background & objectives: Hypertension can be induced by inhibiting nitric oxide synthesis
with L-NAME, which also has a role in oxidative stress. Curcumin has strong antioxidant …

Background The brain stem contains important nuclei that control cardiovascular function via
the sympathetic nervous system (SNS), which is strongly influenced by nitric oxide. Its …