Comparative efficacy and tolerability of pharmacological interventions for acute bipolar depression in adults: a systematic review and network meta-analysis
Background Bipolar depression constitutes a major public health problem due to its
substantial burden of disease. Although pharmacological interventions are available …
substantial burden of disease. Although pharmacological interventions are available …
Lithium treatment over the lifespan in bipolar disorders
C Volkmann, T Bschor, S Köhler - Frontiers in Psychiatry, 2020 - frontiersin.org
Lithium has been the treatment of choice for patients with bipolar disorder (BD) for nearly 70
years. It is recommended by all relevant guidelines as a first-line treatment for maintenance …
years. It is recommended by all relevant guidelines as a first-line treatment for maintenance …
Blood-based biomarkers of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis
Abstract (R, S)-ketamine (ketamine) and its enantiomer (S)-ketamine (esketamine) can
produce rapid and substantial antidepressant effects. However, individual response to …
produce rapid and substantial antidepressant effects. However, individual response to …
[HTML][HTML] Preventing new episodes of bipolar disorder in adults: Systematic review and meta-analysis of randomized controlled trials
A Nestsiarovich, CES Gaudiot, RJ Baldessarini… - European …, 2022 - Elsevier
Uncertainty remains regarding the relative efficacy of maintenance pharmacotherapy for
bipolar disorder (BD), and available data require updating. The present systematic review …
bipolar disorder (BD), and available data require updating. The present systematic review …
Oral ketamine for depression: an updated systematic review
S Meshkat, S Haikazian, JD Di Vincenzo… - The World Journal of …, 2023 - Taylor & Francis
Objectives: Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that can be
used to treat major depressive disorder by single or repeated infusions. However, the …
used to treat major depressive disorder by single or repeated infusions. However, the …
Lithium's antiviral effects: a potential drug for CoViD-19 disease?
A Murru, M Manchia, T Hajek, RE Nielsen… - International Journal of …, 2020 - Springer
Background Since its introduction in modern medicine, naturalistic observations emerged
about possible uses of lithium treatment for conditions different from recurring affective …
about possible uses of lithium treatment for conditions different from recurring affective …
Therapeutic interventions to mitigate mitochondrial dysfunction and oxidative stress–induced damage in patients with bipolar disorder
S Madireddy, S Madireddy - International Journal of Molecular Sciences, 2022 - mdpi.com
Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …
Overview of lithium's use: a nationwide survey
X Perez de Mendiola, D Hidalgo-Mazzei… - International journal of …, 2021 - Springer
Background Lithium is considered the gold standard treatment for bipolar disorder (BD).
Current clinical guidelines and scientific evidence support its use as a first-line treatment in …
Current clinical guidelines and scientific evidence support its use as a first-line treatment in …
Insula activity in resting-state differentiates bipolar from unipolar depression: a systematic review and meta-analysis
M Pastrnak, E Simkova, T Novak - Scientific reports, 2021 - nature.com
Symptomatic overlap of depressive episodes in bipolar disorder (BD) and major depressive
disorder (MDD) is a major diagnostic and therapeutic problem. Mania in medical history …
disorder (MDD) is a major diagnostic and therapeutic problem. Mania in medical history …
Illuminating the way: the role of bright light therapy in the treatment of depression
Introduction Despite the growing number of different therapeutic options, treatment of
depression is still a challenge. A broader perspective reveals the benefits of bright light …
depression is still a challenge. A broader perspective reveals the benefits of bright light …