[HTML][HTML] Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
[HTML][HTML] TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
A Ciesielska, M Matyjek, K Kwiatkowska - Cellular and molecular life …, 2021 - Springer
Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …
Klebsiella pneumoniae infection biology: living to counteract host defences
JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
[HTML][HTML] The endotoxin hypothesis of neurodegeneration
GC Brown - Journal of neuroinflammation, 2019 - Springer
The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or
contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting …
contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting …
Contribution of the intestinal microbiome and gut barrier to hepatic disorders
DM Chopyk, A Grakoui - Gastroenterology, 2020 - Elsevier
Intestinal barrier dysfunction and dysbiosis contribute to development of diseases in liver
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …
Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
[HTML][HTML] Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans
According to the hygiene hypothesis, the increasing incidence of autoimmune diseases in
western countries may be explained by changes in early microbial exposure, leading to …
western countries may be explained by changes in early microbial exposure, leading to …
[HTML][HTML] Key roles of adjuvants in modern vaccines
SG Reed, MT Orr, CB Fox - Nature medicine, 2013 - nature.com
Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …
development and licensing stages, providing new tools to fill previously unmet clinical …
[HTML][HTML] A comparative review of toll-like receptor 4 expression and functionality in different animal species
C Vaure, Y Liu - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) belong to the pattern recognition receptor (PRR) family, a key
component of the innate immune system. TLRs detect invading pathogens and initiate an …
component of the innate immune system. TLRs detect invading pathogens and initiate an …
[HTML][HTML] The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology
SM Huszczynski, JS Lam, CM Khursigara - Pathogens, 2019 - mdpi.com
The major constituent of the outer membrane of Gram-negative bacteria is
lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O …
lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O …