The involvement of natural polyphenols in molecular mechanisms inducing apoptosis in tumor cells: A promising adjuvant in cancer therapy

A Chimento, A De Luca, M D'Amico… - International Journal of …, 2023 - mdpi.com
Various literature data show how a diet rich in vegetables could reduce the incidence of
several cancers due to the contribution of the natural polyphenols contained in them …

Insight into the potential mechanisms of endocrine disruption by Dietary Phytoestrogens in the context of the etiopathogenesis of endometriosis

D Szukiewicz - International Journal of Molecular Sciences, 2023 - mdpi.com
Phytoestrogens (PEs) are estrogen-like nonsteroidal compounds derived from plants (eg,
nuts, seeds, fruits, and vegetables) and fungi that are structurally similar to 17β-estradiol …

[HTML][HTML] Single-cell analysis reveals insights into epithelial abnormalities in ovarian endometriosis

J Yan, L Zhou, M Liu, H Zhu, X Zhang, E Cai, X Xu… - Cell Reports, 2024 - cell.com
Ovarian endometriosis is characterized by the growth of endometrial tissue within the ovary,
causing infertility and chronic pain. However, its pathophysiology remains unclear. Utilizing …

Systemic and local strategies for primary prevention of breast cancer

EK Zaluzec, LF Sempere - Cancers, 2024 - mdpi.com
Simple Summary Current interventions for breast–cancer prevention are associated with
adverse side effects that frequently deter women from selecting these evidence-based risk …

Estrogen receptor subtypes elicit a distinct gene expression profile of endothelial-derived factors implicated in atherosclerotic plaque vulnerability

N Nasiri-Ansari, E Spilioti, I Kyrou… - International Journal of …, 2022 - mdpi.com
In the presence of established atherosclerosis, estrogens are potentially harmful. MMP-2
and MMP-9, their inhibitors (TIMP-2 and TIMP-1), RANK, RANKL, OPG, MCP-1, lysyl …

Prolactin Regulates Ovine Ovarian Granulosa Cell Apoptosis by Affecting the Expression of MAPK12 Gene

R Yang, C Duan, S Zhang, Y Liu, Y Zhang - International Journal of …, 2023 - mdpi.com
Prolactin (PRL) has been reported to influence reproductive performance and cell apoptosis.
However, its mechanism remains unclear. Hence, in the present study, ovine ovarian …

[HTML][HTML] Granulosa cells undergo BPA-induced apoptosis in a mir-21-independent manner

R Sabry, M Williams, J LaMarre, LA Favetta - Experimental cell research, 2023 - Elsevier
Bisphenol A (BPA) is a harmful endocrine disrupting compound that alters not only classical
cellular mechanisms but also epigenetic mechanisms. Evidence suggests that BPA-induced …

Synergistic Anti-Cancer Effects of ERB-041 and Genistein through Estrogen Receptor Suppression-Mediated PI3K/AKT Pathway Downregulation in Canine Mammary …

MJ Yoo, YJ Jang, SY Park, JW Choi… - International Journal of …, 2024 - mdpi.com
Canine-mammary-gland tumors (CMTs) are prevalent in female dogs, with approximately
50% of them being malignant and often presenting as inoperable owing to their size or …

[HTML][HTML] Histology study and transcriptome analysis of the testis of Loach (Misgurnus anguillicaudatus) in response to phenanthrene exposure

N Yang, C Yang, T Tan, Q Wang, X Lei - Ecotoxicology and Environmental …, 2022 - Elsevier
Phenanthrene (PHE) is one of the most abundant polycyclic aromatic hydrocarbon
compounds (PAHs) in the aquatic environment. The loaches were exposed at …

Mechanisms of prostate cancer cells survival and their therapeutic targeting

T Pejčić, Z Todorović, S Đurašević… - International Journal of …, 2023 - mdpi.com
Prostate cancer (PCa) is today the second most common cancer in the world, with almost
400,000 deaths annually. Multiple factors are involved in the etiology of PCa, such as older …