Utilizing animal models of infantile spasms

CG Dulla - Epilepsy Currents, 2018 - journals.sagepub.com
Infantile spasms are a devastating epileptic encephalopathy characterized by early life
spasms and later seizures. Clinical outcomes of infantile spasms are poor and therapeutic …

Acquired parvalbumin‐selective interneuronopathy in the multiple‐hit model of infantile spasms: A putative basis for the partial responsiveness to vigabatrin analogs?

AM Katsarou, Q Li, W Liu, SL Moshé… - Epilepsia …, 2018 - Wiley Online Library
West syndrome, an age‐specific epileptic encephalopathy, manifests with infantile spasms
(IS) and impaired neurodevelopmental outcomes and epilepsy. The multiple‐hit rat model of …

Models and Mechanisms of Epileptic Encephalopathies

AS Galanopoulou - Developmental Epilepsy: From Clinical …, 2019 - books.google.com
Epileptic encephalopathies (EEs) are conditions whereby intense epileptic activity is thought
to adversely impact the functioning of the brain, to a degree far beyond what is expected …