Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

OBJECTIVE To identify published studies quantifying familial prostate cancer risks in
relatives of prostate cancer cases and, by meta‐analysis, obtain more precise estimates of …

BACKGROUND Although narrative reviews have concluded that there is strong support for
familial clustering of prostate carcinoma, the association has never systematically been …

Purpose: We review the current epidemiological and genetic knowledge regarding
hereditary prostate cancer, and outline its clinical implications. Materials and Methods …

Prostate cancer is the most frequent cancer among men in most developed countries, yet
little is known about its causes. Older age, African ancestry and a positive family history of …

Studies on familial aggregation of cancer may suggest an overall contribution of inherited
genes or a shared environment in the development of malignant disease. We performed a …

This article presents an overview of the rapidly evolving body of literature on the
psychological impact of genetic testing for hereditary breast/ovarian cancer susceptibility …

An increased risk of prostate cancer associated with a family history of prostate cancer has
been documented in multiple published reports. Risk has been shown to vary by degree of …

Comparisons of cancer risks in persons by sibling cancers and those by parental cancers
are informative of elucidating the potential genetic modes in the etiology of the cancers. The …

Objectives To test the sensitivity, specificity and accuracy of serum prostate‐specific antigen
isoform [‐2] proPSA (p2PSA),% p2PSA and the prostate health index (PHI), in men with a …